Results 31 to 40 of about 8,175 (178)

Current approaches to the treatment of paraneoplastic encephalitis

Therapeutic Advances in Neurological Disorders, 2011
Paraneoplastic neurological syndromes (PNSs) cover a wide range of diseases and involve both the central nervous system (CNS) and peripheral nervous system.
Wolfgang Grisold, Bruno Giometto, Roberta Vitaliani, Stefan Oberndorfer   +3 more
doaj   +1 more source

Anti‐SOX1 antibody‐positive paraneoplastic neurological syndrome presenting with Lambert‐Eaton myasthenic syndrome and small cell lung cancer: A case report

Thoracic Cancer, 2020
Paraneoplastic neurological syndromes (PNS) are rare disorders affecting any part of the central, peripheral or autonomic nervous system that occur in association with cancer. Among cancer patients, less than 1% overall develop PNS. Anti‐SOX1 antibodies'
Chunyang Li, Xiaolei Wang, Lihua Sun, Hui Deng, Yanqiu Han, Wenqi Zheng   +5 more
doaj   +1 more source

Gastric cancer complicated by paraneoplastic neurological syndrome which presented with extremity numbness: a case report

Surgical Case Reports, 2022
Background Paraneoplastic neurological syndromes refer to a group of neurological disorders, which occur as distant effects of malignant tumors and are not caused by metastasis, nutritional disorders, or side effects of antitumor drugs. Case presentation
Takuto Yoshida, Hideki Kawamura, Kazuhiro Mino, Yuji Konishi, Tomoya Saito, Yuichi Shimizu, Akinobu Taketomi   +6 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Panhypopituitarism as the first sign of paraneoplastic limbic encephalitis in a patient with cured testicular cancer: a case report

Journal of Medical Case Reports, 2022
Background Paraneoplastic limbic encephalitis is a rare neurologic syndrome that affects patients with cancer and commonly presents with symptoms of personality changes, visual disturbances, seizures, vertigo, and memory loss.
Yvonne Lei, Alexandra Milin Glaeser
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

A Rare Case of Sensory Neuropathy Associated with Transitional Cell Carcinoma of the Bladder

Case Reports in Oncology, 2020
Malignancies can trigger an autoimmune response against the nervous system and manifest as paraneoplastic neurological syndromes (PNS). Initial symptoms of PNS may develop up to 5 years prior to the diagnosis of the underlying malignancy.
Sujitha Ketineni, Sreenath Kodali, Sasikanth Gorantla   +2 more
doaj   +1 more source

Paraneoplastic neurological syndromes of the central nervous system: a single institution 7-year case series

Acta Neurologica Belgica, 2023
Paraneoplastic neurological syndromes (PNSs) are nonmetastatic complications of malignancy, defined by the presence of onconeural antibodies (ONAs). ONAs may be found in 60% of patients with central nervous system (CNS) involvement, and they are directed against intraneuronal antigens or channels, receptors or associated proteins located at the ...
Giammello, Fabrizio, Galletta, Karol, Grillo, Francesco, Brizzi, Teresa, Cavallaro, Marco, Mormina, Enricomaria, Scelzo, Emma, Allegra, Cosimo, Stancanelli, Claudia, Rodolico, Carmelo, Musumeci, Olimpia, Toscano, Antonio, Granata, Francesca   +12 more
openaire   +3 more sources

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Paraneoplastic syndromes in childhood neuroblastoma

Journal of Education, Health and Sport
INTRODUCTION: Neuroblastoma is a malignant tumor primarily affecting infants. Originating from embryonic cells of the sympathetic nervous system, NB commonly arises in the adrenal glands, followed by the abdomen, mediastinum, head, and neck.
Natalia Małek, Sara Emerla, Aleksandra Brożyna, Anita Kwiatkowska, Arkadiusz Bydliński, Konrad Karłowicz, Maria Hermanowska, Julia Lubomirska, Patrycja Figurowska, Łukasz Ciulkiewicz, Patryk Pluta   +10 more
doaj   +1 more source