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Neurologic symptoms secondary to a paraneoplastic syndrome may be the presenting manifestation of a previously undiagnosed cancer, and alertness to these syndromes may provide an opportunity for early detection and treatment of a cancer.
Ingrid Yang, Joanna Jaros, Danny Bega
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Neurological manifestation of cancer – paraneoplastic syndromes
Neurological paraneoplastic syndromes (NPS) belong to a heterogeneous group of disorders affecting the nervous system. NPS occur as a result of immunological reaction to the tumor. As a result, the isolated syndrome is formed and manifests itself in many
Szklener Katarzyna, Mandziuk Slawomir
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Introduction. Rapidly progressive cerebellar syndrome (RPCS), previously referred to as “subacute cerebellar degeneration” or “paraneoplastic cerebellar degeneration”, is an autoimmune disorder, wich in the most cases is associated with a malignancy ...
Vera N. Grigoryeva +2 more
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Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer
Paraneoplastic syndromes are a group of rare disorders that can be triggered by an abnormal immune response to proteins from tumors of the lung, ovary, lymphatics, or breast. Paraneoplastic clinical syndromes affect
Madhumita Chatterjee +2 more
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Paraneoplastic syndromes in neuro-ophthalmology
Paraneoplastic neurological syndromes (PNS) occur in about 1 in 300 cases of cancer. The usual mechanism is that an antigen on the cancer sets off an immune response that then cross-reacts with a nervous system antigen. The presentation is usually with a
Simon J Hickman
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Atypical presentation of Non-Hodgkin Lymphoma (NHL): a case report
Lymphomas infrequently cause peripheral nerve complications. These syndromes mostly occur by direct compression or infiltration of nerves (neurolymphomatosis), but may also be due to a remote effect as paraneoplastic syndromes, neurotoxic complications ...
Fabiola Mastropietro +4 more
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Epithelioid hemangioendothelioma (EHE) is a low-grade, malignant vascular neoplasm that frequently involves the liver, lungs, bone, and soft tissue. Although not commonly associated with a paraneoplastic syndrome, paraneoplastic syndromes in the setting ...
Adem Aktas +3 more
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Diffuse Large B-Cell Lymphoma Presenting as an Unusual Paraneoplastic Neurologic Syndrome Affecting the Central and Peripheral Nervous Systems [PDF]
A 68-year-old man presented with a two-week history of ascending, symmetric, sensory neuropathy concerning an acute inflammatory demyelinating polyneuropathy that briefly responded to intravenous immunoglobulin (IVIg) therapy. The initial workup was negative for acquired causes.
Sorrentino, Anthony D +2 more
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Paraneoplastic neurological syndromes (PNS) are remote effects of cancer, which are not caused by invasion of the tumour or its metastasis, but presumably immunologic mediated. They developed in less than 1% of patients with systemic cancers, most Limbic
Goreti Sá +3 more
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Paraneoplastic neurological syndromes (PNSs) are an uncommon complication of cancer, affecting nearby 1/10,000 subjects with a tumour. PNSs can involve all the central and peripheral nervous systems, the muscular system, and the neuromuscular junction ...
Rosario Luca Norrito +8 more
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