Results 11 to 20 of about 10,930 (229)

Paraneoplastic Neurological Syndromes and Beyond Emerging With the Introduction of Immune Checkpoint Inhibitor Cancer Immunotherapy

Frontiers in Neurology, 2021
Paraneoplastic neurological syndromes are more commonly seen with malignancies such as small cell lung cancer, thymoma, gynecological malignancies, and breast cancer as well as seminoma.
Cristina Valencia-Sanchez, Anastasia Zekeridou   +1 more
doaj   +1 more source

Innate and adaptive immunity in human epilepsies [PDF]

, 2017
Inflammatory mechanisms have been increasingly implicated in the origin of seizures and epilepsy. These mechanisms are involved in the genesis of encephalitides in which seizures are a common complaint.
Bauer, J., Becker, A. (Albert), Beghi, C. (Cesare), Elyaman, W. (Wassim), Peltola, J. (Jukka), Rüegg, S. (Stephan), Titulaer, M.J. (Maarten), Varley, J.A. (James A.)   +7 more
core   +6 more sources

Paraneoplastic Neuropathies: What's New Since the 2004 Recommended Diagnostic Criteria

Frontiers in Neurology, 2021
The diagnostic criteria published by the PNS (Paraneoplastic Neurological Syndromes) Euronetwork in 2004 provided a useful classification of PNS, including paraneoplastic neuropathies.
Marco Zoccarato, Wolfgang Grisold, Anna Grisold, Valentina Poretto, Federica Boso, Bruno Giometto, Bruno Giometto   +6 more
doaj   +1 more source

Anti-Ma and anti-Ta associated paraneoplastic neurological syndromes: 22 newly diagnosed patients and review of previous cases [PDF]

, 2008
Background: Paraneoplastic neurological syndromes (PNS) are indirect remote effects of cancer on the nervous system, often associated with the presence of specific serum antibodies.
Hoffmann, L. A., Jarius, S., Johannis, W., Koenig, F., Krumbholz, Markus, La Fougere, Christian, Newman, T., Pellkofer, Hannah Luise, Schueller, M., Vincent, A., Voltz, Raymond   +10 more
core   +1 more source

Paraneoplastic Peripheral Nervous System Manifestations of Renal Cell Carcinoma: A Case Report and Review of the Literature

Case Reports in Neurology, 2017
Neurologic symptoms secondary to a paraneoplastic syndrome may be the presenting manifestation of a previously undiagnosed cancer, and alertness to these syndromes may provide an opportunity for early detection and treatment of a cancer.
Ingrid Yang, Joanna Jaros, Danny Bega
doaj   +1 more source

‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr/DNER, other antibodies, diagnostic pitfalls, summary and outlook [PDF]

, 2015
Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis.
A Bhargava, A McKeon, A McKeon, A Storstein, A Storstein, A Storstein, A Tohgo, A Uchibori, A Vincent, B Balint, B Balint, B Giometto, B Meglic, B. Wildemann, BD Santomasso, C Geis, C Geis, C Geis, C Hida, C Probst, C Sommer, C Steriade, C Totland, C Totland, CF Fletcher, CP Grabner, D Lv, DJ Zack, DS Lim, E Amyes, E Graaff de, E Martin-Garcia, E Seong, E Stark, EB Becker, EJ Dropcho, EJ Dropcho, EL Carpenter, F Aboul-Enein, F Bernal, F Dubois-Galopin, F Graus, F Graus, F Graus, F Keime-Guibert, F Nakatsu, H Fathallah-Shaykh, H Ichikawa, H Nishizumi, H Tomimoto, HJ Altermatt, HJ Altermatt, HJ Okano, HM Furneaux, HM Furneaux, I Rojas, IJ Sutton, IJ Sutton, J Blumstein, J Krakauer, J Matschke, J Thone, J Verschuuren, JC Darnell, JD Debes, JE Greenlee, JE Greenlee, JE Greenlee, JE Greenlee, JE Greenlee, JE Greenlee, JE Hammack, JF Desforges, JL Smith, JL Trotter, JP Corradi, K Bruylant, K Kaida, K Peterson, K Sakai, K Sakai, K Sakai, K Sakai, K Sakai, K Stoeck, K Tanaka, K Tanaka, K Yanase, KA Jaeckle, KE Hill, KJ O’Donovan, L Bataller, LF Borges, LS Newman, M Drlicek, M Eiraku, M Eiraku, M Greene, M Hadjivassiliou, M Ito, M Reindl, M Rodriguez, M Schubert, M Tanaka, M Tanaka, M Uhlen, MJ Fritzler, MJ Titulaer, ML Albert, ML Albert, N Cimolai, N Hansen, NE Anderson, O Stich, O Stich, O Stich, P Widdess-Walsh, R Lundmark, RB Darnell, RB Darnell, RB Darnell, RH Fabian, RH Fabian, RL Longmire, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Jarius, S Mundiyanapurath, S Orrenius, S Phuphanich, S Rauer, S Shams’ili, S Shiraga, S Vernino, S. Jarius, SJ Pittock, T Araki, T Tani, TD Golan, TW Eichler, VA Lennon   +149 more
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Neurological manifestation of cancer – paraneoplastic syndromes

Current Issues in Pharmacy and Medical Sciences, 2021
Neurological paraneoplastic syndromes (NPS) belong to a heterogeneous group of disorders affecting the nervous system. NPS occur as a result of immunological reaction to the tumor. As a result, the isolated syndrome is formed and manifests itself in many
Szklener Katarzyna, Mandziuk Slawomir
doaj   +1 more source

Diagnosis and treatment of paraneoplastic neurological disorders [PDF]

, 2004
In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Graus, F., Voltz, R.
core   +1 more source

Ataxias esporádicas de início no adulto: um desafio diagnóstico [PDF]

, 2014
Patients with adult onset non-familial progressive ataxia are classified in sporadic ataxia group. There are several disease categories that may manifest with sporadic ataxia: toxic causes, immune-mediated ataxias, vitamin deficiency, infectious diseases,
Albuquerque, Marcus Vinicius Cristino De, Barsottini, Orlando Graziani Povoas, Braga Neto, Pedro, Pedroso, José Luiz   +3 more
core   +7 more sources

No evidence for circulating HuD-specific CD8+ T cells in patients with paraneoplastic neurological syndromes and Hu antibodies [PDF]

, 2007
Aim: In paraneoplastic neurological syndromes (PNS) associated with small cell lung cancer (SCLC) and Hu antibodies (Hu-PNS), Hu antigens expressed by the tumour hypothetically trigger an immune response that also reacts with Hu antigens in the nervous ...
Janet W. de Beukelaar, Georges M. Verjans, Yvette van Norden, Johannes C. Milikan, Jaco Kraan, Herbert Hooijkaas, Kees Sintnicolaas, Jan W. Gratama, Peter A. Sillevis Smitt   +8 more
core   +1 more source