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Tropical Spastic Paraparesis on the Caribbean Coast of Colombia
The American Journal of Tropical Medicine and Hygiene, 1995Tropical spastic paraparesis (TSP) is a retroviral disease characterized predominantly by a chronic myelopathy and progressive leg weakness. Four patients from the northern coast of Columbia with chronic spastic paraparesis and serum positivity for antibodies to human T cell lymphotropic virus type 1 by enzyme-linked immunosorbent assay and Western ...
F, Dangond +7 more
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Tropical spastic paraparesis: A neuroepidemiological study in Colombia
Annals of Neurology, 1985AbstractA geographic isolate of tropical spastic paraparesis (TSP) in Tumaco, Colombia, is described. Fifity confirmed cases were identified (29 men, 21 women) with an estimated prevalence rario of 98 cases per 100, 000 population. Patients with identified cases ranged in age from 24 to75 years (mean, 46.5). TSP begins with burning feet, leg stiffness,
G C, Román +3 more
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Archives of Neurology, 2001
T ropical spastic paraparesis (TSP), a progressive myelopathy predominantly affecting the lower limbs, is currently synonymous with human T-lymphotropic virus type I (HTLVI)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). At the turn of the 20th century, Drs Henry Strachan and Henry Scott provided the first clinical descriptions of ...
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T ropical spastic paraparesis (TSP), a progressive myelopathy predominantly affecting the lower limbs, is currently synonymous with human T-lymphotropic virus type I (HTLVI)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). At the turn of the 20th century, Drs Henry Strachan and Henry Scott provided the first clinical descriptions of ...
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Clonus Associated with Tropical Spastic Paraparesis
New England Journal of Medicine, 2016A 53-year-old woman with tropical spastic paraparesis reported several months of worsening weakness of the legs and feet. On examination, she had severe spasticity and weakness of both legs and feet, bilateral Babinski sign, and bilateral patellar clonus, shown in a video.
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Delusional disorder in tropical spastic paraparesis
Irish Journal of Psychological Medicine, 1994AbstractA case of delusional disorder in a patient with the demyelinating disease tropical spastic paraparesis is presented. Only one similar case has previously been described. The implications are discussed.
Ahmed Mahmood +5 more
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The role of HTLV-I in tropical spastic paraparesis in jamaica
Annals of Neurology, 1988We report clinical and laboratory investigations of 47 native-born Jamaican patients with endemic tropical spastic paraparesis and of 1 patient with tropical ataxic neuropathy. Mean age at onset was 40 years, with a female-male preponderance (2.7:1).
P, Rodgers-Johnson +8 more
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Tropical spastic paraparesis treated with Combivir (lamivudine–zidovudine)
Journal of Clinical Neuroscience, 2013Tropical spastic paraparesis (TSP) or human T-cell leukemia virus-type 1 (HTLV-I)-associated myelopathy is caused by human T-lymphotropic virus type 1. It is a slow, progressive spastic paraparesis with significant morbidity and causing profound repercussions on quality of life.
Syed, Hassan, Syed, Amer, Marcus, Zervos
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HTLV-1-associated myelopathy/tropical spastic paraparesis
Nature Reviews Disease Primers, 2015Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the legs, lower back pain and urinary symptoms. HAM/TSP was first described in Jamaica in the nineteenth century, but the aetiology of the condition, infection with the retrovirus ...
Bangham, CRM +3 more
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Tropical spastic paraparesis in Kerala.
Neurology India, 2004Tropical Spastic Paraparesis (TSP) is an uncommon myeloneuropathy with an insular geographic distribution. In 1985, Human T-lymphotropic virus type I (HTLV-1) was reported to be a possible etiological factor. We did an epidemiological, clinical and virological study of 25 cases of TSP.
A, Oomman, M, Madhusoodanan
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Tropical spastic paraparesis in the Seychelles Islands
Neurology, 1987We confirmed the occurrence of endemic tropical spastic paraparesis (TSP) in the Seychelles. Most patients (14/21) were low-income black women. Mean age at onset was 42.8 years (range, 20 to 65). In 62%, onset and progression were slow. Complete paralysis developed in 8/21 (38%) after an evolution of 2 to 15 years.
G C, Román +7 more
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