Rescue axonal defects by targeting mitochondrial dynamics in hereditary spastic paraplegias
Neural Regeneration Research, 2019 Impaired axonal development and degeneration underlie debilitating neurodegenerative diseases including hereditary spastic paraplegia, a large group of inherited diseases.
Yongchao Mou, Xue-Jun Li
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Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]
, 2019 The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F. +4 more
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SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. [PDF]
, 2010 Hereditary spastic paraplegias (HSPs, SPG1-46) are inherited neurological disorders characterized by lower extremity spastic weakness. Loss-of-function SPG20 gene mutations cause an autosomal recessive HSP known as Troyer syndrome.
Bakowska, Joanna C +5 more
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Paraplegic standing supported by FES-controlled ankle stiffness [PDF]
, 2001 The objective of this paper was to investigate whether a paraplegic subject-is able to maintain balance during standing by means of voluntary and reflex activity of the upper body while being supported by closed loop controlled ankle stiffness using FES.
Hunt, K.J., Jaime, R.P., Matjacic, Z.
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The novel de novo mutation of KIF1A gene as the cause for Spastic paraplegia 30 in a Japanese case
eNeurologicalSci, 2019 Spastic paraplegia 30 is a recently established autosomal recessive disease characterized by a complex form of spastic paraplegia associated with neuropathy.
Keisuke Yoshikawa +11 more
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Hydatid Cyst of the Spine: A Rare Case Report
Türkiye Parazitoloji Dergisi, 2022 Hydatid cyst is a zoonotic disease that can affect multiple organs and is difficult to diagnose and treat. Spinal hydatid cyst (SHC) is a rare hydatid cyst involvement observed in 1% of all cases.
Sevil Alkan Çeviker +6 more
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Use of the NESS Handmaster to restore handfunction in tetraplegia: clinical experiences in ten patients [PDF]
, 2000 Objective: To explore possible functional effects of the Handmaster in tetraplegia and to determine suitable patients for the system. \ud \ud Patients: Patients with a cervical spinal cord injury between C4 and C6, motor group 0-3.
Groen, F.A.C.G. in 't +4 more
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Further supporting evidence for REEP1 phenotypic and allelic heterogeneity. [PDF]
, 2019 Heterozygous mutations in REEP1 (MIM #609139) encoding the receptor expression-enhancing protein 1 (REEP1) are a well-recognized and relatively frequent cause of autosomal dominant hereditary spastic paraplegia (HSP), SPG31.1 REEP1 localizes in the ...
Behnam, M +5 more
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Case Report: Anesthetic Management of Cesarean Section in a Patient With Paraplegia
Frontiers in Medicine, 2022 BackgroundWith the advancement of medical science and rehabilitative care, more women with spinal cord injury (SCI) can conceive. However, autonomic hyperreflexia due to SCI complicates anesthesia management during cesarean sections.Case PresentationThis
Yongchun Su, Xiaofeng Lei, Jin Yu
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Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation [PDF]
, 2017 Background: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with ...
Aikawa +34 more
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