Results 61 to 70 of about 54,988 (248)
Frontiers in Veterinary Science, 2019 Paraparesis and paraplegia are common conditions in dogs, most often caused by a disc herniation in the thoracolumbar spinal segments (T3-L3), which is a neurological emergency.
Fernando Swiech Bach +10 more
doaj +1 more source
Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa +3 more
wiley +1 more source
Spinal Cord, 1973 A clinical impression of a significant difference in the incidence of pain among spinal paralytics at two Spinal Centres, one in Australia, the other in the United States, has been substantiated by a survey of the patients of the two Centres. A detailed analysis of the possible factors explaining this difference in the incidence of pain was carried out
openaire +2 more sources
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Einstein (São Paulo)Paraplegia is a well-defined state of complete motor deficit in lower limbs, regardless of sensory involvement. The cause of paraplegia usually guides treatment, however, some controversies remain about the time and benefits for spinal cord decompression
Leonardo Giacomini +5 more
doaj +1 more source
Hyperactive KIF5A in Neurodegeneration
Cytoskeleton, EarlyView.ABSTRACT The highly polarised morphology of neurons and the sheer length of their axons make transport of cargoes throughout the cell a formidable task. Decades of evidence obtained from genetic studies on patients and animal models highlight deficits in axonal transport as a recurrent cause, or early contributing factor, in a plethora of ...
David Villarroel‐Campos +1 more
wiley +1 more source
Effect of rehabilitation timing on the functional, vocational, and psychological outcomes in patients with paraplegia secondary to traumatic spinal cord injury: a retrospective cohort study [PDF]
Asian Spine JournalStudy Design A retrospective cohort study. Purpose To study the effect of rehabilitation timing on the functional, psychological, and vocational outcomes of patients with paraplegia secondary to traumatic spinal cord injury (SCI).
R Dinesh Iyer +8 more
doaj +1 more source
Hereditary spastic paraplegia: Novel insights into the pathogenesis and management
SAGE Open MedicineHereditary spastic paraplegia is a genetically heterogeneous neurodegenerative disorder characterised primarily by muscle stiffness in the lower limbs. Neurodegenerative disorders are conditions that result from cellular and metabolic abnormalities, many
Wireko Andrew Awuah +18 more
doaj +1 more source
Pyonephrosis in paraplegia [PDF]
Spinal Cord, 1970 A report is given on 32 cases of pyonephrosis encountered over 17 years in paraplegic and tetraplegic patients. Its relation to neurological lesions and its time of onset, the clinical picture and the surgical treatment and results are discussed. Views are expressed on the value of conservative surgical treatment.
openaire +2 more sources