Paraparesis and paraplegia are common conditions in dogs, most often caused by a disc herniation in the thoracolumbar spinal segments (T3-L3), which is a neurological emergency.
Fernando Swiech Bach +10 more
doaj +1 more source
Familly with two different cases of post- and pre-natal L1 syndrome; When hydrocephaly become "multidisciplinary headache" [PDF]
open11openBukvic, Nenad; Boaretto, Francesca; Loverro, Giuseppe; Susca, Francesco C.; Lovaglio, Rosaura; Patruno, Margherita; Bukvic, Dragoslav; Starcevic, Srdjan; Vazza, Giovanni; Mostaciuollo, Maria Luisa; Resta, NicolettaBukvic, Nenad; Boaretto ...
Boaretto, Francesca +10 more
core +1 more source
Unraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics
ABSTRACT TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.
Teresa Zhao +122 more
wiley +1 more source
Research on non-invasive monitoring of biomechanical and viscoelastic properties of the myotendinous complex in patients with paraplegia post spinal cord injury (SCI), in sub-acute period, in order to streamline the neurorecovery proces - A systematic literature review [PDF]
The disabling nature of SCI influences the most important aspects of a patient`s life in the long term, but also their quality of life, thus placing an important responsibility on the medical staff to achieve a satisfactory level of recovery and ...
Alexandra-Mădălina Sporici +2 more
doaj +1 more source
A novel mouse model simulating C5 palsy after cervical surgery
This study establishes a reliable mouse model of permanent C5 palsy (post‐laminectomy complication) via dorsal approach, selectively severing the C5 anterior nerve root while preserving the posterior root through partial C4 and C5 laminectomy. The model successfully replicates clinical C5P features—flaccid shoulder paralysis, electrophysiological ...
Chenpei Xu +8 more
wiley +1 more source
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov +42 more
wiley +1 more source
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller +15 more
wiley +1 more source
Effect of rehabilitation timing on the functional, vocational, and psychological outcomes in patients with paraplegia secondary to traumatic spinal cord injury: a retrospective cohort study [PDF]
Study Design A retrospective cohort study. Purpose To study the effect of rehabilitation timing on the functional, psychological, and vocational outcomes of patients with paraplegia secondary to traumatic spinal cord injury (SCI).
R Dinesh Iyer +8 more
doaj +1 more source
New opportunities for bioscaffold‐enabled spinal cord injury repair
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi +11 more
wiley +1 more source
Investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord injury [PDF]
This article provides the outcome of an investigation of robotics-assisted tilt-table therapy for early-stage rehabilitation in spinal cord ...
Allan, David +4 more
core +1 more source

