Results 141 to 150 of about 2,036,812 (336)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Genome sequence of the human malaria parasite Plasmodium falciparum

Nature, 2002
M. Gardner, N. Hall, E. Fung, O. White, M. Berriman, R. Hyman, J. Carlton, A. Pain, K. Nelson, S. Bowman, I. Paulsen, K. James, J. Eisen, Kim M Rutherford, S. Salzberg, A. Craig, S. Kyes, Man-Suen Chan, V. Nene, Shamira J. Shallom, Bernard B. Suh, J. Peterson, Samuel V. Angiuoli, M. Perțea, Jonathan E. Allen, J. Selengut, D. Haft, M. Mather, A. Vaidya, David M. A. Martin, A. Fairlamb, M. Fraunholz, D. Roos, S. Ralph, G. McFadden, L. Cummings, G. Subramanian, C. Mungall, J. Venter, D. Carucci, S. Hoffman, C. Newbold, Ronald W. Davis, C. Fraser, B. Barrell   +44 more
semanticscholar   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Nanoimprinted DMD Electrodes Enabling Bidirectional Viewing OLEDs With Quasi Lambertian Emission

Advanced Science, EarlyView.
We present a dual‐approach strategy for high‐performance bidirectional‐viewing OLEDs, combining enhanced cavity resonance with a nanoimprinted dielectric/metal/dielectric (DMD) electrode. This bidirectional viewing OLED presents an 89.7% enhanced electrode transmittance, a balanced bidirectional emission ratio with 67.3% total brightness increase, as ...
Ningning Song, Ningning Liang, Xinghao Guo, Ruixiang Chen, Xia Xin, Yiming Chen, Ruiqi Tian, Tianrui Zhai   +7 more
wiley   +1 more source

Critical Limitations in Cryogenic Laser Cooling of Solids: Symmetry‐Related Fluorescence Trapping and Condensation‐Induced Parasitic Heating

Advanced Science, EarlyView.
This study uncovers two overlooked bottlenecks in cryogenic laser cooling of solids: symmetry‐driven fluorescence trapping and water vapor condensation. We demonstrate that breaking sample symmetry enhances fluorescence escape, while condensation dominates parasitic heating below 135 K.
Biao Zhong, Jiayi Zhang, Haodong Yang, Lianzhong Deng, Mauro Tonelli, Ercang Luo   +5 more
wiley   +1 more source

Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor

Advanced Science, EarlyView.
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid, Usman Safder, Sobia Ali Khan, Anh‐Tuan Pham, Muhammad Sheeraz, Nguyen‐Hoang Dang, Duy Le Thanh, Zeeshan Tahir, Faisal Maqbool, Koo‐Hyun Chung, Sunglae Cho, Jungdae Kim, Yong Soo Kim   +12 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of Leishmania major in Mice [PDF]

, 2020
Brombacher, F., Hurdayal, R., Khutlang, R., Nieuwenhuizen, N.   +3 more
core   +2 more sources