Results 101 to 110 of about 52,532 (272)
Background: The bark of Chrysophyllum albidum is reported to possess antimalarial property. The fruit pulp of C. albidum consumed by pregnant women of south eastern Nigeria may also possess antimalarial activity.
Chibueze Peter Ihekwereme +3 more
doaj +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Aims Resistance to the artemisinins and the artemisinin‐based combination therapy (ACT) partner drugs has developed in Southeast Asia, and artemisinin resistance has also emerged in eastern Africa. Triple ACTs (triple artemisinin‐based combination therapies, TACT), consisting of two partner drugs with different mechanisms of action and similar ...
Junjie Ding +24 more
wiley +1 more source
To confirm that Beagle dogs are a good experimental model for Chagas disease, we evaluated hematological alterations during the acute and chronic phases in Beagle dogs infected with the Y, Berenice-78 (Be-78) and ABC strains of Trypanosomacruzi ...
Paulo Marcos Matta Guedes +10 more
doaj +1 more source
Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
core +1 more source
Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel +9 more
wiley +1 more source
ABSTRACT Objective Malaria and anaemia are significant public health challenges among young children in Burkina Faso, with complex interactions between climate variability, food security, and nutrient deficiencies. This study aimed to identify the malariometric profile and nutrient patterns among young children and to determine the associations of ...
Adi Lukas Kurniawan +8 more
wiley +1 more source
Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Anneli Cooper +19 more
core +1 more source
Probing the effects of increased protein intake on Plasmodium berghei parasitemia level in Swiss Webster mice [PDF]
Muhammad Jiofansyah +4 more
openalex +1 more source
Melshew Fenta,1 Wubayehu Kahaliw2 1University of Gondar Specialized Referral Teaching Hospital, University of Gondar, Gondar, Ethiopia; 2Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar,
Fenta M, Kahaliw W
doaj

