Results 11 to 20 of about 52,532 (272)

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Magez, Stefan, Stijlemans, Benoit, Van Ginderachter, Jo A   +6 more
core   +1 more source

Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]

, 2018
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo, Brown, Lauren E., Cencic, Regina, Crandall, Ian, Gros, Philippe, Kain, Kevin C., Kennedy, James M., Langlais, David, Moradin, Neda, Pelletier, Jerry, Porco, John A., Schmeing, Martin, Tarry, Michael J.   +12 more
core   +1 more source

How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]

, 2013
BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena, Cardoni, Rita Liliana, de Rissio, Ana María, Perrone, Alina Elizabeth, Ruiz, Andrés Mariano, Scollo, Karenina, Velázquez, Elsa Beatriz, Volta, Bibiana Julieta   +7 more
core   +3 more sources

The Impact of Submicroscopic Parasitemia on Malaria Rapid Diagnosis in Northeastern Tanzania, an Area with Diverse Transmission Patterns

Infectious Disease Reports, 2022
Global malaria epidemiology has changed in the last decade with a substantial increase in cases and deaths being recorded. Tanzania accounts for about 4% of all cases and deaths reported in recent years.
Robert Diotrephes Kaaya, Johnson Matowo, Debora Kajeguka, Filemoni Tenu, Boniface Shirima, Franklin Mosha, Reginald Kavishe   +6 more
doaj   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida, Andrade, Antunez, Aune, Avilan, Bern, Cardillo, Carlier, Carnaud, Cesari, Collins, Culbertson, Dowling, Duthie, Duthie, Duthie, Filtjens, Fraser, Frosch, Gritz, Hanke, Keating, Lieke, Lieke, Mekkawy, Meyer Zum Buschenfelde, Mondino, Nagata, Nogueira, Pettengill, Pinazo, Rassi, Robertson, Rottenberg, Santana, Sardinha, Stevenaert, Taveirne, Torrico, Truyens, Truyens, Truyens, Une, Van Beneden, Van Beneden, Van Den Broeck, Van Den Broeck, Vassalli, Wen   +48 more
core   +2 more sources

Trypanosoma cruzi Infection at the Maternal-Fetal Interface: Implications of Parasite Load in the Congenital Transmission and Challenges in the Diagnosis of Infected Newborns

Frontiers in Microbiology, 2019
Trypanosoma cruzi is the protozoan unicellular parasite that causes Chagas disease. It can be transmitted from infected mothers to their babies via the connatal route, thus being able to perpetuate even in the absence of Triatomine insect vectors. Chagas
Patricia L. Bustos, Natalia Milduberger, Natalia Milduberger, Bibiana J. Volta, Alina E. Perrone, Susana A. Laucella, Jacqueline Bua, Jacqueline Bua   +7 more
doaj   +1 more source

Natural regulatory (CD4+CD25+FOXP+) T cells control the production of pro-inflammatory cytokines during Plasmodium chabaudi adami infection and do not contribute to immune evasion. [PDF]

, 2008
Different functions have been attributed to natural regulatory CD4+CD25+FOXP+ (Treg) cells during malaria infection. Herein, we assessed the role for Treg cells during infections with lethal (DS) and non-lethal (DK) Plasmodium chabaudi adami parasites ...
Belanger, B, Cambos, M, Jacques, A, Roulet, A, Scorza, T   +4 more
core   +1 more source

Biology of Trypanosoma cruzi strains isolated from chagasic patients from different geographic origins residing in northwestern region of the state of Paraná, Brazil

Acta Scientiarum: Biological Sciences, 2008
Trinta e uma cepas de Trypanosoma cruzi isoladas de pacientes chagásicos de diferentes origens geográficas e residentes no noroeste do Paraná foram analisadas pelos parâmetros biológicos: infectividade das formas de cultura, perfil das curvas de ...
Silvana Marques de Araújo, Ana Lúcia Falavigna Guilherme, Max Jean de Ornelas Toledo, Paulo José Gamba de Oliveira, José Carlos da Silva, Mônica Lúcia Gomes   +5 more
doaj   +1 more source

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E, Graham, Andrea L, Lamb, Tracey J, Read, Andrew F   +3 more
core   +3 more sources

Enhancing the efficacy of anti-malarial drugs with immune boosters: A mathematical model

AIMS Allergy and Immunology, 2023
This paper presents a mathematical model of severe malarial anemia (SMA), which is a complication of malaria and is a major contributor to malaria-related deaths. SMA is characterized by a decrease in hemoglobin levels in the blood due to the suppression
Dorcas Mulenga, Winnie Anoumedem, Blessing O. Emerinini, Nourridine Siewe   +3 more
doaj   +1 more source