How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]
, 2013 BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena +7 more
core +10 more sources
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
, 2020 Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
core +1 more source
Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model [PDF]
, 2016 Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies.
Baro, Nicholas +14 more
core +1 more source
The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]
, 2016 The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida +48 more
core +2 more sources
Acta Scientiarum: Biological Sciences, 2008 Trinta e uma cepas de Trypanosoma cruzi isoladas de pacientes chagásicos de diferentes origens geográficas e residentes no noroeste do Paraná foram analisadas pelos parâmetros biológicos: infectividade das formas de cultura, perfil das curvas de ...
Silvana Marques de Araújo +5 more
doaj +1 more source
Trypanosoma brucei brucei is more pathogenic in rats compared to mice, making rats a better candidate for the relevant research studies [PDF]
The Iranian Journal of Veterinary Science and Technology, 2021 Trypanosomosis is an economically important disease that has raised great and diverse kinds of research using different types of animals. Hence, this study is aimed at determining the better laboratory animal between the Swiss albino mice and Wistar ...
Karimat Hussain +4 more
doaj +1 more source
Parasitemia and its daily variation in canine leishmaniasis [PDF]
Parasitology Research, 2020 The aim of this study was to evaluate, through qPCR, the prevalence of parasitemia in sick kennel dogs naturally infected by canine leishmaniasis. An evaluation of daily changes of the parasitic load in peripheral blood was also performed. A comprehensive clinical examination and the collection of several samples (blood, lymph node, skin, and ...
Simona Di Pietro +6 more
openaire +3 more sources
Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]
, 2005 Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E +3 more
core +3 more sources
Malaria parasitemia among blood donors in Uganda
Transfusion, 2020 BACKGROUNDMalaria remains a leading transfusion associated infectious risk in endemic areas. However, the prevalence of malaria parasitemia has not been well characterized in blood donor populations. This study sought to determine the prevalence of Plasmodium in red blood cell (RBC) and whole blood (WB) units after the rainy season in Uganda.METHODS ...
Kristin J. Murphy +13 more
openaire +3 more sources
Reduced parasitemia observed with erythrocytes containing inositol hexaphosphate [PDF]
Antimicrobial Agents and Chemotherapy, 1988 Chemicals entrapped in erythrocytes by hypotonic hemolysis can be assessed for possible antiparasitic activity both in vivo and in vitro, regardless of whether they are able to diffuse into erythrocytes readily. Inositol hexaphosphate, a highly charged compound, produced a dramatic lowering of the percentage of cells infected by Babesia microti in vivo
C L, Mintzer +7 more
openaire +2 more sources