Results 61 to 70 of about 1,112,965 (337)

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

The influence of temperature and humidity on the flight activity of Culicoides imicola both under laboratory and field conditions

Parasites & Vectors, 2019
Background Insight into the factors that regulate the circadian host-seeking flight activity of Culicoides vectors (Diptera: Ceratopogonidae) will be of importance to assess the risk of transmission of Culicoides-borne pathogens.
Gert J. Venter, Solomon N. B. Boikanyo, Chantel J. de Beer   +2 more
doaj   +1 more source

Parasites of the Spotted Sucker, Minytrema melanops (Cypriniformes: Catostomidae) from Arkansas and Oklahoma [PDF]

, 2018
During October 2015, March and April 2016 and again between March and April 2017, 15 Spotted Sucker (Minytrema melanops) were collected from sites in the Ouachita (n = 5), Red (n = 1), and St.
Choudhury, Anindo, Cloutman, Donald G, Fayton, Thomas J, McAllister, Chris T., Robison, Henry W., Scholz, Tomas, Trauth, Stanley E.   +6 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Fitness estimates from experimental infections predict the long-term strain structure of a vector-borne pathogen in the field

Scientific Reports, 2017
The populations of many pathogen species consist of a collection of common and rare strains but the factors underlying this strain-specific variation in frequency are often unknown.
Jonas Durand, Maxime Jacquet, Olivier Rais, Lise Gern, Maarten J. Voordouw   +4 more
doaj   +1 more source

Validation of loop-mediated isothermal amplification for the detection of Loa loa infection in Chrysops spp in experimental and natural field conditions

Parasites & Vectors, 2021
Background The mass drug administration of ivermectin for onchocerciasis control has contributed to a significant drop in Loa loa microfilaria loads in humans that has, in turn, led to reduction of infection levels in Chrysops vectors.
Glory Ngongeh Amambo, Raphael Awah Abong, Fanny Fri Fombad, Abdel Jelil Njouendou, Franck Nietcho, Amuam Andrew Beng, Ritter Manuel, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Peter Ivo Enyong, Catherine Poole, Achim Hoerauf, Clotilde Carlow, Samuel Wanji   +14 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]

, 2019
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K., Magez, Stefan, Stijlemans, Benoit   +2 more
core   +2 more sources

The development of malaria parasites in the mosquito midgut

Cellular Microbiology, 2016
The mosquito midgut stages of malaria parasites are crucial for establishing an infection in the insect vector and to thus ensure further spread of the pathogen.
Sandra Bennink, Meike J. Kiesow, G. Pradel   +2 more
semanticscholar   +1 more source