Results 31 to 40 of about 308,225 (311)

ANALYSIS OF CIRCULATING STRAINS, CAUSING INVASIVE LISTERIOSIS IN BULGARIA FOR TEN YEARS, 2010-2019

open access: yesProblems of Infectious and Parasitic Diseases, 2020
Listeriosis is a zoonosis with multiple mechanisms of infection and multiple organ symptoms, severe course and high lethality. An increasing incidence of listeriosis has been reported in several European countries in recent years.
Evgeniya Taseva   +5 more
doaj   +1 more source

Kinetoplastids: related protozoan pathogens, different diseases. [PDF]

open access: yes, 2008
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Gürtler, Ricardo E   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Areas of Echinococcosis From the Qinghai-Tibet Plateau Extend to Yunnan: An Observation of Deworming and Control Integrated Impact Evaluation on Dogs

open access: yesJournal of Parasitology Research
Conclusions: In areas with low prevalence of echinococcosis, the village with positive dogs shall take measures for the management of RMDD, STDA, and SDFD and perform deworming four times a year.
Ben-Fu Li   +10 more
doaj   +1 more source

COMPARISON OF AUTOMATED AND MANUAL DNA EXTRACTION METHODS IN ISOLATING ENTEROBIUS VERMICULARIS DNA.

open access: yesProblems of Infectious and Parasitic Diseases
The aim of the present study was to compare automated and manual DNA extraction method from Enterobius vermicularis (human pinworm) eggs. Materials and methods: Scotch tape samples positive for Enterobius vermicularis eggs via microscopic examination,
Mihaela Videnova   +9 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

IMMUNOBLOT REACTIVITIES OF DIFFERENT LYME DISEASE SPECIFIC ANTIGENS TO ANTI-BORRELIA BURGDORFERI IgG ANTIBODIES

open access: yesProblems of Infectious and Parasitic Diseases
Background: Lyme disease is a vector-borne disease with increasing incidences in last years. It is the most common tick-borne infection in Bulgaria, caused by Borrelia burgdorferi sensu lato (Bbsl) complex after a bite from Ixodes ricinus tick.
Teodora Gladnishka   +6 more
doaj   +1 more source

GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

open access: yesFrontiers in Immunology, 2019
Toxoplasma gondii causes infections in a wide range of intermediate hosts and remains a threatening disease worldwide because of the lack of effective drugs and vaccines.
Bin Zheng   +13 more
doaj   +1 more source

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