Results 41 to 50 of about 2,646,118 (304)

Parasitic crustaceans in fishes from some Philippine Lakes [PDF]

, 2001
Parasitic crustaceans are among the most harmful parasites of fishes. Certain species cause disease outbreaks and mortalities in aquaculture, facilities, and sometimes in natural systems, resulting in serious economic losses.
Lopez, Nellie C.
core   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources

IMMUNOBLOT REACTIVITIES OF DIFFERENT LYME DISEASE SPECIFIC ANTIGENS TO ANTI-BORRELIA BURGDORFERI IgG ANTIBODIES

Problems of Infectious and Parasitic Diseases
Background: Lyme disease is a vector-borne disease with increasing incidences in last years. It is the most common tick-borne infection in Bulgaria, caused by Borrelia burgdorferi sensu lato (Bbsl) complex after a bite from Ixodes ricinus tick.
Teodora Gladnishka, Iva Trifonova, Kim Ngoc, Vladislava Ivanova, Elitsa Panayotova, Evgenia Taseva, Iva Christova   +6 more
doaj   +1 more source

Parasitism as a Factor in Disease [PDF]

Science, 1921
n ...
openaire   +2 more sources

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

The Virulence-Related MYR1 Protein of Toxoplasma gondii as a Novel DNA Vaccine Against Toxoplasmosis in Mice

Frontiers in Microbiology, 2019
Toxoplasma gondii causes serious public health problems, but there is no effective treatment strategy against it currently. DNA vaccines have shown promising findings in this regard. MYR1 is a new virulence factor identified in T.
Bin Zheng, Bin Zheng, Jianzu Ding, Jianzu Ding, Di Lou, Di Lou, Qunbo Tong, Qunbo Tong, Xunhui Zhuo, Xunhui Zhuo, Haojie Ding, Haojie Ding, Qingming Kong, Qingming Kong, Shaohong Lu, Shaohong Lu   +15 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Molecular characterization and B-cell epitope analysis of the TSP11 gene in Echinococcus infection strains from Yunnan Province

Parasitology
This study investigates the molecular intricacies of the transmembrane protein TSP11 gene in Echinococcus strains isolated from livestock and patients in Yunnan Province afflicted with Echinococcus granulosus (E. granulosus) between 2016 and 2020.
Qian Xu, Zhengqing Wang, Jinrong Zi, Xuan Cai, Fangwei Wu, Benfu Li, Jia Peng, Jianxiong Li, Xinliu Yan, Ying Dong, Yaming Yang   +10 more
doaj   +1 more source

GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

Frontiers in Immunology, 2019
Toxoplasma gondii causes infections in a wide range of intermediate hosts and remains a threatening disease worldwide because of the lack of effective drugs and vaccines.
Bin Zheng, Bin Zheng, Di Lou, Di Lou, Jianzu Ding, Jianzu Ding, Xunhui Zhuo, Xunhui Zhuo, Haojie Ding, Haojie Ding, Qingming Kong, Qingming Kong, Shaohong Lu, Shaohong Lu   +13 more
doaj   +1 more source