ISONIAZID - MONORESISTANT TUBERCULOSIS IN BULGARIA
Background. Isoniazid is a common drug in the treatment regimens for TB infection. Monoisoniazid resistance reduces the probability of a successful treatment outcome and increases the risk of acquiring additional drug resistance. Material and methods.
Stanislava Yordanova +4 more
doaj +1 more source
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]
Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M. +4 more
core +1 more source
ANNUAL ANALYSIS OF PARASITIC INFECTIONS IN BULGARIA IN 2022
INTRODUCTION: Infections caused by parasites still represent an important global health problem. Although parasitic infections are responsible for significant morbidity and mortality in developing countries, they are also prevalent in developed ...
Rumen Harizanov +9 more
doaj +1 more source
Conclusions: In areas with low prevalence of echinococcosis, the village with positive dogs shall take measures for the management of RMDD, STDA, and SDFD and perform deworming four times a year.
Ben-Fu Li +10 more
doaj +1 more source
ANALYSIS OF CIRCULATING STRAINS, CAUSING INVASIVE LISTERIOSIS IN BULGARIA FOR TEN YEARS, 2010-2019
Listeriosis is a zoonosis with multiple mechanisms of infection and multiple organ symptoms, severe course and high lethality. An increasing incidence of listeriosis has been reported in several European countries in recent years.
Evgeniya Taseva +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Proteomic Identification and Functional Analysis of Babesia microti Reveals Heparin-Binding Proteins
Glycosaminoglycan (GAG) molecules on the surface of red blood cells play an important regulatory role in the invasion of merozoites of apicomplexan protozoa.
Yu Chun Cai +9 more
doaj +1 more source
COMPARISON OF AUTOMATED AND MANUAL DNA EXTRACTION METHODS IN ISOLATING ENTEROBIUS VERMICULARIS DNA.
The aim of the present study was to compare automated and manual DNA extraction method from Enterobius vermicularis (human pinworm) eggs. Materials and methods: Scotch tape samples positive for Enterobius vermicularis eggs via microscopic examination,
Mihaela Videnova +9 more
doaj +1 more source
Central limit approximations for Markov population processes with countably many types [PDF]
When modelling metapopulation dynamics, the influence of a single patch on the metapopulation depends on the number of individuals in the patch. Since there is usually no obvious natural upper limit on the number of individuals in a patch, this leads to ...
Barbour, A. D., Luczak, M. J.
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

