Results 41 to 50 of about 259,963 (295)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Molecular characterization and B-cell epitope analysis of the TSP11 gene in Echinococcus infection strains from Yunnan Province

Parasitology
This study investigates the molecular intricacies of the transmembrane protein TSP11 gene in Echinococcus strains isolated from livestock and patients in Yunnan Province afflicted with Echinococcus granulosus (E. granulosus) between 2016 and 2020.
Qian Xu, Zhengqing Wang, Jinrong Zi, Xuan Cai, Fangwei Wu, Benfu Li, Jia Peng, Jianxiong Li, Xinliu Yan, Ying Dong, Yaming Yang   +10 more
doaj   +1 more source

Mortality rate and prognostic factors for poor outcome in HIV-infected Bulgarian patients with Pneumocystis pneumonia over a 3-year period

Problems of Infectious and Parasitic Diseases, 2020
Background: In spite of the use of combination antiretroviral therapy and specific prophylaxis, Pneumocystis pneumonia remains one of the most common AIDS-defining disease with high mortality rate.
Nina Yancheva, Dimitar Strashimirov, Maria Nikolova, Ivailo Alexiev, Aleksandra Ivanova, Nina Tsvetkova   +5 more
doaj   +1 more source

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

DISTRIBUTION OF MYCOBACTERIUM AVIUM COMPLEX IN BULGARIA

Problems of Infectious and Parasitic Diseases, 2018
The members of Mycobacterium avium complex (MAC) are opportunistic microorganisms, common in the environment (soil and water) and cause infections in birds, mammals and humans.
Yuliana Atanasova, Stanislava Yordanova, Yana Todorova, Ana Baikova, Elizabeta Bachiyska   +4 more
doaj   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

The Virulence-Related MYR1 Protein of Toxoplasma gondii as a Novel DNA Vaccine Against Toxoplasmosis in Mice

Frontiers in Microbiology, 2019
Toxoplasma gondii causes serious public health problems, but there is no effective treatment strategy against it currently. DNA vaccines have shown promising findings in this regard. MYR1 is a new virulence factor identified in T.
Bin Zheng, Bin Zheng, Jianzu Ding, Jianzu Ding, Di Lou, Di Lou, Qunbo Tong, Qunbo Tong, Xunhui Zhuo, Xunhui Zhuo, Haojie Ding, Haojie Ding, Qingming Kong, Qingming Kong, Shaohong Lu, Shaohong Lu   +15 more
doaj   +1 more source

Detachable and Reusable: Reinforced π‐Ion Film for Modular Synaptic Reservoir Computing

Advanced Materials, EarlyView.
This study presents a reinforced π‐ion film for organic electrochemical transistors (OECTs), addressing the rapid degradation of organic semiconductor layers. By introducing a mesh support and utilizing a scalable solvent exchange method, the π‐ion film enhances detachability and stability.
Gyu Won Woo, Chang Min Lee, Won Woo Lee, Min Ju Jung, Seung Min Lee, Hye Won Lee, Hocheon Yoo, Yong Hee Kim, Eun Kwang Lee   +8 more
wiley   +1 more source

SURVEILLANCE DATA ON BACTERIAL ENTEROCOLITIS IN BULGARIA FOR 2014-2018

Problems of Infectious and Parasitic Diseases, 2019
Worldwide, 30% of cases of infectious diarrhoea are caused by bacterial pathogens. As in other countries of the European Union, in Bulgaria the most common etiological agents are Escherichia coli (STEC), Salmonella spp., Shigella spp., Campylobacter spp.
Maria Pavlova, V. Velev, Miroslav Karageorgiev, Ekaterina Alexandrova, E. Kamenov, Todor Kantardjiev   +5 more
doaj   +1 more source

DYNAMICS OF THE ETIOLOGICAL STRUCTURE OF SALMONELLOSIS IN BULGARIA AND SENSITIVITY TO ANTI‐BACTERIAL AGENTS FOR THE PERIOD 2016 – 2019

Problems of Infectious and Parasitic Diseases, 2020
Background. In recent years, some features of salmonellosis have been noted: an increase in morbidity all around the world, which is accompanied by an increase in the number of isolated serotypes from humans, animals and food; an increase in sporadic ...
Maria Pavlova, Galin Kamenov, Ekaterina Alexandrova, Valeri Velev, Todor Kantardjiev   +4 more
doaj   +1 more source