Results 71 to 80 of about 13,284,007 (349)

GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

Frontiers in Immunology, 2019
Toxoplasma gondii causes infections in a wide range of intermediate hosts and remains a threatening disease worldwide because of the lack of effective drugs and vaccines.
Bin Zheng, Bin Zheng, Di Lou, Di Lou, Jianzu Ding, Jianzu Ding, Xunhui Zhuo, Xunhui Zhuo, Haojie Ding, Haojie Ding, Qingming Kong, Qingming Kong, Shaohong Lu, Shaohong Lu   +13 more
doaj   +1 more source

Interleukin (IL)-21 in Inflammation and Immunity During Parasitic Diseases

Frontiers in Cellular and Infection Microbiology, 2019
Parasitic diseases cause significant morbidity and mortality in the developing and underdeveloped countries. No efficacious vaccines are available against most parasitic diseases and there is a critical need for developing novel vaccine strategies for ...
S. Solaymani-Mohammadi, L. Eckmann, S. Singer   +2 more
semanticscholar   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Pests/parasites and diseases of milkfish in the Philippines [PDF]

, 1984
This paper presents all known parasites of milkfish (Chanos chanos ) in the Philippines. The major parasitic groups include acanthocephalans, copepods, isopods, and heterophyid flukes. The number of parasitic species found in ponds is small compared with
Velasquez, Carmen C.
core   +1 more source

Molecular characterization and B-cell epitope analysis of the TSP11 gene in Echinococcus infection strains from Yunnan Province

Parasitology
This study investigates the molecular intricacies of the transmembrane protein TSP11 gene in Echinococcus strains isolated from livestock and patients in Yunnan Province afflicted with Echinococcus granulosus (E. granulosus) between 2016 and 2020.
Qian Xu, Zhengqing Wang, Jinrong Zi, Xuan Cai, Fangwei Wu, Benfu Li, Jia Peng, Jianxiong Li, Xinliu Yan, Ying Dong, Yaming Yang   +10 more
doaj   +1 more source

The Virulence-Related MYR1 Protein of Toxoplasma gondii as a Novel DNA Vaccine Against Toxoplasmosis in Mice

Frontiers in Microbiology, 2019
Toxoplasma gondii causes serious public health problems, but there is no effective treatment strategy against it currently. DNA vaccines have shown promising findings in this regard. MYR1 is a new virulence factor identified in T.
Bin Zheng, Bin Zheng, Jianzu Ding, Jianzu Ding, Di Lou, Di Lou, Qunbo Tong, Qunbo Tong, Xunhui Zhuo, Xunhui Zhuo, Haojie Ding, Haojie Ding, Qingming Kong, Qingming Kong, Shaohong Lu, Shaohong Lu   +15 more
doaj   +1 more source

Health-related quality of life among school children with parasitic infections : findings from a national cross-sectional survey in Côte d'Ivoire [PDF]

, 2014
Parasitic infections are still of considerable public health relevance, notably among children in low- and middle-income countries. Measures to assess the magnitude of ill-health in infected individuals, however, are debated and patient-based proxies ...
Silué, Kigbafori D., Eveline Hürlimann, Utzinger, Jürg, Yapi, Richard B., Ferdinand N Kouamé, Ferdinand N. Kouamé (573277), Clarisse A Houngbedji, Richard B. Yapi (424490), Prisca B Ndri, Richard B Yapi, Gotianwa Soro (573276), Jürg Utzinger, Houngbedji, Clarisse A., Giovanna Raso, Giovanna Raso (51489), Ndri, Prisca B., Prisca B. Ndri (573275), Raso, Giovanna, Eliézer K. N'Goran (108853), Gotianwa Soro, Clarisse A. Houngbedji (573274), Jürg Utzinger (39609), Eveline Hürlimann (217729), Thomas Fürst (128978), Kigbafori D. Silué (128980), Kouamé, Ferdinand N., Eliézer K N'Goran, Thomas Fürst, Soro, Gotianwa, N'Goran, Eliézer K., Hürlimann, Eveline, Kigbafori D Silué, Fürst, Thomas   +32 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

PHYLOGENETIC ANALYSIS OF TWELVE BULGARIAN SEQUENCES BASED ON PARTIAL OPEN READING FRAME 2 GENOME FRAGMENT OF HEPATITIS E VIRUS

Problems of Infectious and Parasitic Diseases
Background: Hepatitis E virus (HEV) causes both acute and chronic liver inflammation. HEV is transmitted through the fecal-oral mechanism and infects both animals and humans.
Chiydem Ismailova, Asq Stoyanova, Viliana Yoncheva, Tencho Tenev, Lubomira Nikolaeva-Glomb, Elitsa Golkocheva-Markova   +5 more
doaj   +1 more source

Immune responses result in misdiagnosis of Schistosoma japonicum by immunodiagnosis kits in egg-positive patients living in a low schistosomiasis transmission area of China

Parasites & Vectors, 2014
Background In recent field surveys, we failed to detect the presence of specific antibody against Schistosoma japonicum in some egg-positive patients by commonly used immunodiagnostic kits.
Shu-Ying Xie, Min Yuan, Min-Jun Ji, Fei Hu, Zhao-Jun Li, Yue-Min Liu, Xiao-Jun Zeng, Hong-Gen Chen, Hai-Wei Wu, Dan-Dan Lin   +9 more
doaj   +1 more source