Results 171 to 180 of about 1,847,937 (304)

Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection. [PDF]

Proc Natl Acad Sci U S A
Chen G, Jun JH, Wijshake T, Kwarteng EO, Li Y, Yuan M, Rose J, Li S, Cobb S, Serpa W, Folger B, Li Y, Li L, Chen W, Collins JJ, Wang J, Agathocleous M.   +16 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Use of Bioelectrical Impedance Analysis to Measure the Impact of Parasitic Infection on Goat Sperm Quality. [PDF]

Animals (Basel)
Shahat AM, Narlagiri R, Siddique A, Chelkapally SC, Kolikapongu RS, Namani SC, Shaik A, Batchu P, Gurrapu P, Erukulla TT, Neha A, Terrill TH, Moawad AR.   +12 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

The influence of parasitic infection (Eimeria spp.) on bone and cartilage tissue in an animal model. [PDF]

Sci Rep
Tomczyk-Warunek A, Muszyński S, Tomaszewska E, Dobrowolski P, Arczewska-Włosek A, Świątkiewicz S, Józefiak D.   +6 more
europepmc   +1 more source

Parasitic Infection and Immunity-A Special Biomedicines Issue. [PDF]

Biomedicines, 2022
Pereira MA, Santos-Gomes G.
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Parasitic Infection and Host Immunity, 2nd Edition. [PDF]

Microorganisms
Freire-de-Lima CG.
europepmc   +1 more source

Advances in research on autophagy in the maintenance of insect–microbe symbiosis

New Plant Protection, EarlyView.
Autophagy plays a dual regulatory role in insect–microbe symbiotic relationships. Beneficial symbiotic bacteria in insects participate in nutrient exchange via the TOR pathway, whereas pathogenic microbes induce immune defense through the AMPK pathway. Autophagy‐related genes regulate development and pathogen clearance during this process.
Yanbin Wang, Yuqiong Hao, Ke Chen, Hongbin Zhang, Xiansheng Xie, Feirong Ren   +5 more
wiley   +1 more source

Frequency of Intestinal Parasitic Infection and Associated Factors Among HIV Patients on Antiretroviral Therapy at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A 5-Year Retrospective Study. [PDF]

J Trop Med
Tegegne D, Kebede M, Tegegne G, Abateneh Y, Kiros T, Erkihun M, Almaw A, Assefa A, Berhan A, Fentie A, Tiruneh T, Malkamu B, Feyisa MS, Legese B, Getu S, Meberat MW, Getie B, Damtie S, Sharew B, Abeje G.   +19 more
europepmc   +1 more source