Results 1 to 10 of about 38,275 (219)

Pharmacokinetics of Albendazole, Albendazole Sulfoxide, and Albendazole Sulfone Determined from Plasma, Blood, Dried-Blood Spots, and Mitra Samples of Hookworm-Infected Adolescents

open access: yesAntimicrobial Agents and Chemotherapy, 2019
Albendazole is an effective anthelmintic intensively used for decades. However, profound pharmacokinetic (PK) characterization is missing in children, the population mostly affected by helminth infections.
Anna Neodo   +2 more
exaly   +3 more sources

Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis.

open access: yesPLoS Neglected Tropical Diseases, 2022
BackgroundAlbendazole is an orally administered anti-parasitic medication with widespread usage in a variety of both programmatic and clinical contexts.
Charles Whittaker   +6 more
doaj   +2 more sources

High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

open access: yesFrontiers in Pharmacology, 2021
Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. It has been described that the administration with meals increases albendazole absorption. Our aim was to compare
Dolores Ochoa   +12 more
doaj   +2 more sources

Drug Resistance Assessment of Commonly Used Anthelmintics, and Their Combination Effect in Naturally Infected Sheep: The Case of Kaffa Zone, Southwestern Ethiopia. [PDF]

open access: yesVet Med Sci
This study evaluated the efficacy of widely used commercial anthelmintics and examined whether combining different drug classes enhances their effectiveness in naturally infected sheep in the Kaffa Zone. This study suggest the presence of emerging anthelmintic resistance to albendazole and tetramisole in the study area and highlight the potential ...
Belay N, Arke A, Tesfaye L.
europepmc   +2 more sources

Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

open access: yesPLoS Neglected Tropical Diseases, 2018
BackgroundThe soil-transmitted helminths (STH), Ascaris lumbricoides, Trichuris trichiura and hookworms, infect 1.5 billion people worldwide and cause an estimated burden of 3.3 million disability-adjusted life years (DALYs).
Marta S Palmeirim   +8 more
doaj   +2 more sources

Combined high-quality metagenomics reveals off-target effects of albendazole, ivermectin-albendazole and moxidectin-albendazole on the human gut bacteria [PDF]

open access: yesnpj Biofilms and Microbiomes
Human whipworm infections caused by Trichuris trichiura and Trichuris incognita remain a major public health problem, affecting over 400 million people globally and responding poorly to standard benzimidazole chemotherapy.
Julian Dommann   +7 more
doaj   +2 more sources

Evaluation of the Protoscolicidal Effects of Albendazole and Albendazole Loaded Solid Lipid Nanoparticles

open access: yesIranian Journal of Parasitology, 2019
Background: Protoscolex plays an important role in the development of hydatid cyst. Albendazole is one of the most effectual protoscolicidal agents for averting the reappearance of this disease, nonetheless, its low solubility and its low intestinal ...
Shohreh AMINPOUR   +3 more
doaj   +2 more sources

Punica granatum and amygdalin extracts plus cobalamin combined with albendazole reduce larval burden and myositis in experimental trichinosis

open access: yesRevista Brasileira de Parasitologia Veterinária, 2021
Trichinellosis is a zoonosis results from eating raw or semi-cooked meat of infected animals. Medicinal plants have been used lately as alternatives and/or combined therapies to resolve some drawbacks of the current regimens.
Marwa Esmat   +8 more
doaj   +1 more source

Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update

open access: yesKorean Journal of Parasitology, 2021
The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed.
J. Chai, Bong-Kwang Jung, Sung-Jong Hong
semanticscholar   +1 more source

CURCUMIN IN TREATMENT OF EXPERIMENTAL TRICHINOSIS [PDF]

open access: yesJournal of the Egyptian Society of Parasitology, 2023
Trichinella spiralis is one of the most widespread zoonotic parasitic nematodes in theworld. There is an increasing interest in developing new safe and effective anthelminthic herbaldrug against T. spiralis.
HEBA ABOELELA   +5 more
doaj   +1 more source

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