Results 21 to 30 of about 16,923 (158)

Effect of Sambucus Ebulus Extract and Erythromycin on Albendazole-Induced Histomorphometric Changes in Placenta of Rat

مجله دانشکده پزشکی اصفهان, 2018
Background: There are some reports that albendazole passes placenta and causes disorders in fetus. Besides, there is some evidence that the effect apparently is related to its active metabolite, albendazole sulfoxide.
Mahmood Khaksary-Mahabady, Reza Ranjbar, Hossein Najafzadeh-Varzi, Hasan Morovvati, Elnaz Lak   +4 more
doaj   +1 more source

Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. [PDF]

PLoS ONE, 2014
Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. No method is currently available for measuring albendazole and its metabolites in silkworm hemolymph.
Li Li, Dong-Xu Xing, Qing-Rong Li, Yang Xiao, Ming-Qiang Ye, Qiong Yang   +5 more
doaj   +1 more source

Evaluation of the efficacy of Zataria multiflora essential oil versus albendazole in patients infected with liver cystic echinococcosis: A nonrandomized clinical trial

Journal of Research in Medical Sciences, 2021
Background: Cystic echinococcosis (CE) is a life-threatening disease in many countries. Albendazole, as the drug of choice for medical treatment of CE, is accompanied by adverse effects and may be ineffective in 20%–40% of cases; hence, new and more ...
Arash Jafari, Mohammad Moazeni, Seyed Vahid Hosseini, Hajar Khazraei, Saeedeh Pourahmad   +4 more
doaj   +1 more source

Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice

Biomolecules, 2020
Currently, Angiostrongylus cantonensis infections are predominantly treated with albendazole. However, the use of albendazole can provoke certain neurological symptoms as a result of the immune response triggered by the dead worms.
Ho Yin Pekkle Lam, Ting-Ruei Liang, Shinn-Jong Jiang, Shih-Yi Peng   +3 more
doaj   +1 more source

Drug Induced Liver Injury by Prophylactic Administration of Albendazole

The Korean Journal of Gastroenterology, 2019
Albendazole is used as a typical antiparasitic agent worldwide. The side effects of albendazole may include nausea, vomiting, abdominal pain, dizziness, headache, alopecia, and increased liver enzymes. Mild elevation of the liver enzyme has been reported
Sang Yi Moon, Yang Hyun Baek, Sung Wook Lee   +2 more
doaj   +1 more source

Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for
Noemi Cowan, Charles Meier, Anna Neodo, Jennifer Keiser   +3 more
doaj   +1 more source

Pharmacokinetic Characterization and Comparative Bioavailability of an Innovative Orodispersible Fixed-Dose Combination of Ivermectin and Albendazole: A Single Dose, Open Label, Sequence Randomized, Crossover Clinical Trial in Healthy Volunteers

Frontiers in Pharmacology, 2022
Soil-transmitted helminths are intestinal worm diseases transmitted through the soil. Available treatments are albendazole and/or ivermectin. The co-administration of existing drugs is an appropriate strategy.
Jaime Algorta, Alejandro Krolewiecki, Alejandro Krolewiecki, Filipe Pinto, Silvia Gold, Jose Muñoz   +5 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Melatonin in Combination with Albendazole or Albendazole Sulfoxide Produces a Synergistic Cytotoxicity against Malignant Glioma Cells through Autophagy and Apoptosis

Brain Sciences, 2023
Glioblastoma is the most aggressive and lethal brain tumor in adults, presenting diffuse brain infiltration, necrosis, and drug resistance. Although new drugs have been approved for recurrent patients, the median survival rate is two years; therefore ...
Miguel Hernández-Cerón, Víctor Chavarria, Camilo Ríos, Benjamin Pineda, Francisca Palomares-Alonso, Irma Susana Rojas-Tomé, Helgi Jung-Cook   +6 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source