Results 11 to 20 of about 1,008 (150)

Interactions of some parasympatholytics and structurally related drugs with acetylcholinesterases. Kinetic studies

, 2022
S.1719-1726The interactions of the parasympatholytics adiphenine, adiphenine H, propantheline and the structurally related compounds diphenhydramine, D-propoxyphene and methadone with acetylcholinesterases were studied by means of kinetic measurements ...
Haller, R., Wiegand, U.-W., Kuhnen, H.
core   +1 more source

Chinese clinical practice guidelines for the prevention and treatment of radiation‐induced rectal injury

Precision Radiation Oncology, Volume 7, Issue 4, Page 237-255, December 2023., 2023
The implementation of efficient preventative measures can improve the quality of life. Preventive measures mainly focus on patient education, optimization of radiotherapy techniques (such as IMRT, IGRT, et al.), physical protection measures (injecting hyaluronic acid and collagen, inflatable balloon catheter), and pharmacological interventions (such as
Hui Zhang, Zhen Zhang, Shuanghu Yuan
wiley   +1 more source

Medication clusters at hospital discharge and risk of adverse drug events at 30 days postdischarge: A population‐based cohort study of older adults

British Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3715-3752, December 2023., 2023
Aims Certain combinations of medications can be harmful and may lead to serious adverse drug events (ADEs). Identifying potentially problematic medication clusters could help guide prescribing and/or deprescribing decisions in hospital. The aim of this study is to characterize medication prescribing patterns at hospital discharge and determine which ...
Daniala L. Weir, Xiaomeng Ma, Lisa McCarthy, Terence Tang, Lauren Lapointe‐Shaw, Walter P. Wodchis, Olavo Fernandes, Emily G. McDonald   +7 more
wiley   +1 more source

Bilateral corneal ulceration in a cat after general anaesthesia

Veterinary Record Case Reports, Volume 11, Issue 3, September 2023., 2023
Abstract General anaesthesia is accompanied by a loss of the blink reflex, decreased tear production, inability to close the eye and decreased stability of the tear film. Protection of the eye with corneal lubricant is standard during general anaesthesia, but clear recommendations are missing.
Sebastian Thenhaus‐Schnabel, Teresa Bilotta, Christine Watte, Olivier Louis Levionnois   +3 more
wiley   +1 more source

Semaglutide delays 4‐hour gastric emptying in women with polycystic ovary syndrome and obesity

Diabetes, Obesity and Metabolism, Volume 25, Issue 4, Page 975-984, April 2023., 2023
Abstract Aim To evaluate the effect of once‐weekly subcutaneous semaglutide 1.0 mg on the late digestive period of gastric emptying (GE) after ingestion of a standardized solid test meal by using technetium scintigraphy, the reference method for this purpose.
Mojca Jensterle, Simona Ferjan, Luka Ležaič, Aljaž Sočan, Katja Goričar, Katja Zaletel, Andrej Janez   +6 more
wiley   +1 more source

Sila-Pharmaca, 31 th Communication [1] Synthesis, Structure, and Pharmacological Properties of Diphenyl(2-piperidinoethoxymethyl)silanol and its Carbon Analogue

, 1983
In the course of systematic investigations on sila-substituted parasympatholytics the diphenyl(2-aminoethoxymethyl)silanols 3b and 4b (and its carbon analogue 4a) were synthesized and characterized by their physical and chemical properties.
Lange, Hartwig, Tacke, Reinhold, Moser, Ulrich, Lambrecht, Günter, Sheldrick, William S., Mutschler, Ernst   +5 more
core   +2 more sources

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

THE EFFECT OF NEUROPHARMACOLOGIC AGENTS UPON BLADDER AND URETHRA: PROSTAGLANDIN, PARASYMPATHOLYTICS AND ALPHA ADRENERGIC BLOCKADE [PDF]

, 1981
The effect of neuropharmacologic agents upon the function of bladder and urethra has been investigated. Prostaglandins (PGs) were intravenously given to female mongrel dogs to evaluate their potencies to evacuate the urine. PGE series were found superior
近藤, 厚生
core  

Parkinson's Disease and Salivary Issues: A Survey

Gerodontology, Volume 43, Issue 2, Page 234-244, June 2026.
ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk, Merel C. Verhoeff, Niels van der Aa, Frank Lobbezoo   +3 more
wiley   +1 more source

Association Between Cholinesterase Inhibitor‐Overactive Bladder Antimuscarinic Prescribing Cascade and Risk of Delirium and Falls Among Individuals Living With Dementia

Journal of the American Geriatrics Society, Volume 74, Issue 5, Page 1314-1325, May 2026.
ABSTRACT Background Prescribing cascades occur when cholinesterase inhibitor (ChEI)‐induced urinary incontinence is misinterpreted as a new condition, leading to overactive bladder (OAB) antimuscarinic initiation. We evaluated whether the ChEI‐OAB antimuscarinic prescribing cascade was associated with delirium or falls compared with mirabegron in older
Sarah Beth Tucker, Bryan L. Love, Chijioke M. Okeke, Erin D. Zwick, Chengwen Teng, Jingkai Wei, Ibraheem M. Karaye, Saud Alsahali, Krithika Rajagopalan, Ismaeel Yunusa   +9 more
wiley   +1 more source