Idiopathic functional urinary outflow tract obstruction in dogs, a retrospective case series (2010‐2021): 31 cases [PDF]
Background Idiopathic functional urinary outflow tract obstruction (iFUOTO) is an uncommon but life‐limiting disease whose etiology and clinical course of disease remain poorly understood.
Kathrina Mathews+4 more
doaj +2 more sources
Management of Urinary Incontinence With Underactive Bladder: A Review [PDF]
Urinary incontinence is caused by storage function failure, while underactive bladder (UAB) is caused by a decline in detrusor contractility and voiding dysfunction.
Kang Jun Cho, Joon Chul Kim
doaj +2 more sources
The association between prescription drugs and colorectal cancer prognosis: a nationwide cohort study using a medication-wide association study [PDF]
Background With the availability of health insurance claim data, pharmacovigilance for various drugs has been suggested; however, it is necessary to establish an appropriate analysis method.
Hyeong-Taek Woo+2 more
doaj +2 more sources
Involvement of substance P (SP) and its related NK1 receptor in primary Sjögren’s syndrome (pSS) pathogenesis [PDF]
Primary Sjogren's Syndrome (pSS) is a systemic autoimmune disease that primarily attacks the lacrimal and salivary glands, resulting in impaired secretory function characterized by xerostomia and xerophthalmia.
Antonio Greco+11 more
core +2 more sources
Potentially inappropriate drug use in myasthenia gravis: a real-world population-based cohort study in Italy [PDF]
Introduction: To evaluate the use of pyridostigmine in presence of contraindications, and the use of concomitant potentially contraindicated drugs in a cohort of patients affected by Myasthenia Gravis (MG) in the Italian Regions of Lazio, Tuscany, and ...
Addis, Antonio+9 more
core +2 more sources
The use of a percutaneous cystostomy tube as an adjunctive treatment option for dogs with idiopathic functional outflow tract obstruction. [PDF]
Abstract Background Functional outflow tract obstruction (FOO) remains a challenging disease to manage in male dogs. Cystostomy tubes have been used to relieve urethral obstruction while allowing time to achieve effective medical management, avoiding the need for emergency visits and repeat urinary catheterizations.
Greenfield ZP, Berent AC, Weisse CW.
europepmc +2 more sources
Neuroscience in peripheral cancers: tumors hijacking nerves and neuroimmune crosstalk. [PDF]
The figure depicts the intricate interactions between cancer cells, the immune system, and nerves within the tumor microenvironment. At the center, the diagram highlights the tripartite relationship among cancer, immune, and nerve cells, illustrating the dynamic and reciprocal influences they exert on one another.
Fan HY, Liang XH, Tang YL.
europepmc +2 more sources
Drug Use Patterns in Myasthenia Gravis: A Real-World Population-Based Cohort Study in Italy [PDF]
Background: In the context of a comparative study of efficacy and safety of drugs used in rare neuromuscular and neurodegenerative diseases (CAESAR-call AIFA_FV_2012-13-14), we assessed the use patterns of drugs indicated for myasthenia gravis (MG ...
Crescioli, Giada+2 more
core +5 more sources
Background Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa).
Paulo L. Pfitzinger+17 more
doaj +1 more source
The Dependence of Urinary Bladder Responses on Extracellular Calcium Varies Between Muscarinic, Histamine, 5-HT (Serotonin), Neurokinin, Prostaglandin, and Angiotensin Receptor Activation [PDF]
With many common bladder diseases arising due to abnormal contractions, a greater understanding of the receptor systems involved may aid the development of future treatments.
Chess-Williams, Russ+2 more
core +1 more source