Results 31 to 40 of about 872 (151)

Allopregnanolone as an Adjunct Therapy to Midazolam is More Effective Than Midazolam Alone in Suppressing Soman‐Induced Status Epilepticus in Male Rats

CNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.
Acute poisoning with the organophosphate, soman, triggers status epilepticus that rapidly becomes refractory to standard of care treatment with midazolam (MDZ). Combined treatment with MDZ and allopregnanolone (ALLO) significantly suppresses seizure activity, which is associated with attenuated neurodegeneration and neuroinflammation.
Peter M. Andrew, Jeremy A. MacMahon, Xiuzhen Liu, Naomi H. Saito, Kyle E. Berger, Julia E. Morgan, Ashish Dhir, Danielle J. Harvey, Hilary S. McCarren, Michael A. Rogawski, Pamela J. Lein   +10 more
wiley   +1 more source

Is it time for a new choice of treatments for underactive bladder?

A range of mechanisms and systems underly urinary bladder contractions. However, when contraction is inhibited, such as with underactive bladder (UAB), it is not always clear which mechanism is at fault.
Moro, Christian, Phelps, Charlotte, Veer, Vineesha   +2 more
core   +2 more sources

Bayliss Starling Prize Lecture 2023: Neuropeptide‐Y being ‘unsympathetic’ to the broken hearted

The Journal of Physiology, Volume 603, Issue 7, Page 1841-1864, 31 March 2025.
Abstract figure legend The hallmark of cardiac disease is autonomic dysregulation, characterised by a state of chronic sympathoexcitation. Neuropeptide‐Y (NPY) is a sympathetic co‐transmitter that is released by sympathetic neurons and circulating venous levels are elevated in a range of cardiac disease, such as myocardial infarction and chronic heart ...
Benjamin Bussmann, Thamali Ayagama, Kun Liu, Dan Li, Neil Herring   +4 more
wiley   +1 more source

Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects

The Journal of Physiology, Volume 603, Issue 7, Page 1865-1885, 31 March 2025.
Abstract figure legend Summary of strategies in modelling neurocardiac interactions using human pluripotent stem cells. Abstract Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the body's ever‐changing metabolic needs. This vital function is continuously regulated by the autonomic nervous system.
Hsueh‐Fu Wu, Charlotte Hamilton, Harrison Porritt, Annika Winbo, Nadja Zeltner   +4 more
wiley   +1 more source

Innervation and secretory function of transplanted human submandibular salivary glands

, 2008
Free submandibular gland autotransplantation is used to treat absolute tear deficiency. Although disconnected from any peripheral innervation, most transplants show increasing secretion for years.
Paterson, K L, Sieg, P, Lauer, I, Geerling, G, Carpenter, G H; id_orcid, Garrett, J R, Collin, J R O, Hakim, S G, Proctor, G B   +8 more
core   +1 more source

CLINICAL STUDIES OF DRUG-INDUCED RETENTION [PDF]

, 1982
Thirty-five patients with urinary retention caused by various medicines were seen during the last 2 years. They were 30 males and 5 females; 74% of them were over 60 years.
小谷, 俊一, 瀧田, 徹, 近藤, 厚生, 三矢, 英輔   +3 more
core  

Совместимость системных препаратов и местной гипотензивной терапии у пациентов с первичной открытоугольной глаукомой (аналитический обзор) [PDF]

, 2019
The prevalence of glaucoma in the world today is extremely high: according to different authors total prevalence number reach as high as 66 to 105 million people.
A. S. Makarova, А. С. Макарова, В. П. Еричев, V. P. Erichev   +3 more
core   +1 more source

Порівняння курсових доз протиглаукомних препаратів у DDD /на рік/ на 1 хворого та їх вартості для вибору ефективного та економічно доступного лікування [PDF]

, 2014
The aim of the study was to determine the need in antiglaucoma drugs in non-monetary and monetary terms per a patient for one year of treatment using the ATC/DDD methodology.
Kryvoviaz, S. O., Makarenko, O. V., Kryvoviaz, O. V.   +2 more
core   +1 more source

Parasempatomimetiklerin antinosiseptif etkisi

, 2001
ÖZET Parasempatomimetiklerin Antinosiseptif Etkisi Çalışmamızda parasempatomimetikleri sistemik yoldan uygulayarak analjezik olarak kullanmak üzere yeni bir yöntem geliştirilmesi amaçlanmıştır.
SEVGİ BÜYÜKYILDIZ EMİNEL
core  

Auto-modulation of release of pharmacological mediators of immediate (type I) hypersensitivity. A review

LR: 20041117; PUBM: Print; JID: 0213341; 0 (Autacoids); 0 (Kinins); 0 (Parasympathomimetics); 0 (Prostaglandins); 0 (SRS-A); 0 (Sympathomimetics); 50-67-9 (Serotonin); 51-61-6 (Dopamine); RF: 92; ppublishSource type: Electronic ...

core   +1 more source