Central Nervous System-Active Medications and Risk of Hospital Readmission in Older Multimorbid Adults. [PDF]
J Am Geriatr SocABSTRACT Background Polypharmacy is associated with adverse outcomes, particularly in older multimorbid adults. However, little is known about the negative outcomes associated with multiple central nervous system (CNS)‐active medications that are commonly prescribed to these patients. Objective To assess the association between the number of CNS‐active
Stuber MJ +10 more
europepmc +2 more sources
Current pharmacological and surgical treatment of underactive bladder [PDF]
Tzu Chi Medical Journal, 2017 Underactive bladder (UAB) or detrusor underactivity (DU) is a common yet still poorly understood urological problem. In addition to true detrusor failure and neuropathy, the inhibitory effects of detrusor contraction by the striated urethral sphincter ...
Yuan-Hong Jiang +3 more
doaj +2 more sources
Underactive bladder - an underestimated entity [PDF]
, 2020 Introduction. The concept of underactive bladder is relatively new. Currently there is no generally accepted definition of this pathology. Diagnosis depends on urodynamic findings, and symptoms are usually rare and intricated with the symptoms of other ...
Bratu, Ovidiu Gabriel +8 more
core +4 more sources
Effects of Omidenepag Isopropyl Versus Latanoprost Eye Drops on Intraocular Pressure, Pupil Diameter, and Anterior Chamber Parameters in Normal Feline Eyes: A Pilot Study. [PDF]
Vet OphthalmolABSTRACT Objectives This study aimed to compare the effect of the newly developed selective prostaglandin E2 receptor agonist, omidenepag isopropyl (OMDI), and latanoprost on intraocular pressure (IOP), pupil diameter (PD), and anterior chamber parameters in normal feline eyes.
Park SE +5 more
europepmc +2 more sources
Journal of Experimental & Clinical Cancer Research, 2020 Background Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa).
Paulo L. Pfitzinger +17 more
doaj +1 more source
Detrusor underactivity: To tone or not to tone the bladder?
Indian Journal of Urology, 2009 Objectives: The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity. Materials& Methods: We searched all relevant data from Medline and peer-
Sriram Krishnamoorthy, Nitin S Kekre
doaj +1 more source
The Dependence of Urinary Bladder Responses on Extracellular Calcium Varies Between Muscarinic, Histamine, 5-HT (Serotonin), Neurokinin, Prostaglandin, and Angiotensin Receptor Activation [PDF]
, 2022 With many common bladder diseases arising due to abnormal contractions, a greater understanding of the receptor systems involved may aid the development of future treatments.
Chess-Williams, Russ +2 more
core +1 more source
Ageing and the bladder mucosa: A scoping review of recent animal model studies [PDF]
, 2022 The incidence of lower urinary tract symptoms increases with age. People with bladder disorders who are older than 60 years are more likely to comply and persist with treatment regimens, such as antimuscarinic medications for overactive bladder ...
Moro, Christian, Phelps, Charlotte
core +1 more source
Unlicensed and off-label prescription of respiratory drugs to children [PDF]
, 2004 Many respiratory drugs are not available in formulations suitable for infants and toddlers. Efficacy and safety research is mostly restricted to older children.
Anker, J.N. (John) van den +4 more
core +3 more sources
Ageing influences detrusor contractions to prostaglandin, angiotensin, histamine and 5-HT (serotonin), independent to the Rho kinase and extracellular calcium pathways [PDF]
, 2023 Ageing is associated with deteriorating urinary bladder function and an increasing prevalence of disorders such as underactive bladder. There are suggestions that G protein-coupled receptor (GPCR) second messenger pathways are altered during ageing ...
Chess-Williams, Russ +2 more
core +1 more source