Results 131 to 140 of about 174,955 (289)
Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
The FEBS Journal, EarlyView.MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley +1 more source
IL-6 regulates the polarization of Dectin-1 macrophages to weaken immune escape in thyroid cancer
Journal of Translational MedicineBackground Immune evasion is a critical barrier to effective treatment of thyroid carcinoma (TC). Macrophage polarization plays a pivotal role in shaping the tumor microenvironment (TME). This study aimed to elucidate how IL-6 regulates Dectin-1–mediated
Xianzhao Deng +5 more
doaj +1 more source
Risk Factors for Falls in Patients on Hemodialysis: A 12‐Month Prospective Study
Hemodialysis International, EarlyView.ABSTRACT Background Patients on hemodialysis have comorbidities and malnutrition and are subject to polypharmacy, which contributes to disability and sarcopenia. These conditions increase the risk of falls and are associated with fractures, morbidities, substantial costs, nursing home admissions, hospitalization, and mortality.
Luciana Angélica da Silva de Jesus +10 more
wiley +1 more source
The control of calcium metabolism by parathyroid hormone, calcitonin and vitamin D [PDF]
Advances in analysis of chemistry and physiology of parathyroid hormone, calcitonin, and Vitamin D are described along with development of techniques in radioassay methods.
Potts, J. T., Jr.
core +1 more source
Five Advances in the Last 50 Years That Have Impacted Endocrine Surgery
World Journal of Surgery, EarlyView.
Matilda Anneback +5 more
wiley +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey +4 more
wiley +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall +4 more
wiley +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source