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Best Practice & Research Clinical Endocrinology & Metabolism, 2018
Parathyroid carcinoma (PC) is a rare disease with an indolent behavior due to the low malignant potential. The etiology is unknown. Somatic mutations of CDC73 gene, the same gene involved in the hyperparathyroidism-jaw tumor syndrome, can be identified in up to 70% of patients with PC and in one-third of cases the mutations are germline.
Antonio Stefano, Salcuni +7 more
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Parathyroid carcinoma (PC) is a rare disease with an indolent behavior due to the low malignant potential. The etiology is unknown. Somatic mutations of CDC73 gene, the same gene involved in the hyperparathyroidism-jaw tumor syndrome, can be identified in up to 70% of patients with PC and in one-third of cases the mutations are germline.
Antonio Stefano, Salcuni +7 more
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Australian and New Zealand Journal of Surgery, 1999
Parathyroid cysts are relatively uncommon. They may be non‐functioning or associated with primary hyperparathyroidism. Three patients are presented, including one with a large mediastinal parathyroid cyst, and these cases illustrate the range of pathological and clinical features.
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Parathyroid cysts are relatively uncommon. They may be non‐functioning or associated with primary hyperparathyroidism. Three patients are presented, including one with a large mediastinal parathyroid cyst, and these cases illustrate the range of pathological and clinical features.
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Diagnostic Cytopathology, 1986
AbstractCytologic criteria for diagnosing parathyroid adenomas and hyperplasia have not been elucidated. This report will present the cytomorphology of parathyroid tissue in the spectrum of normal, hyperplastic, and neoplastic states. We examined clinical needle aspirates from three patients with parathyroid lesions as well as 15 needle aspirations or ...
D D, Davey, M D, Glant, E K, Berger
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AbstractCytologic criteria for diagnosing parathyroid adenomas and hyperplasia have not been elucidated. This report will present the cytomorphology of parathyroid tissue in the spectrum of normal, hyperplastic, and neoplastic states. We examined clinical needle aspirates from three patients with parathyroid lesions as well as 15 needle aspirations or ...
D D, Davey, M D, Glant, E K, Berger
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Endocrine Practice, 2011
To review the current knowledge pertaining to the etiology, molecular pathogenesis, and management of parathyroid carcinoma, a rare presentation of primary hyperparathyroidism.The existing MEDLINE English-language literature was reviewed using the search terms "parathyroid" and "carcinoma" or "cancer."Parathyroid cancer is a rare endocrine tumor ...
Sandy H, Fang, Geeta, Lal
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To review the current knowledge pertaining to the etiology, molecular pathogenesis, and management of parathyroid carcinoma, a rare presentation of primary hyperparathyroidism.The existing MEDLINE English-language literature was reviewed using the search terms "parathyroid" and "carcinoma" or "cancer."Parathyroid cancer is a rare endocrine tumor ...
Sandy H, Fang, Geeta, Lal
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The “parathyroid blush” in the identification of parathyroid glands
The American Journal of Surgery, 1974Abstract When part of a parathyroid gland is excised for biopsy, the cut surface remaining becomes diffusely red from microscopic bleeding in one to three seconds, the “parathyroid blush.” By this simple observation the surgeon can distinguish grossly similar structures such as lobular fat from parathyroid tissue.
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Journal of Surgical Oncology, 2005
AbstractParathyroid carcinoma is an uncommon malignancy. It accounts for less than 1% of cases of primary hyperparathyroidism (HPT). It is manifested by severe hypercalcemia and up to 50% of patients will have concomitant kidney or bone disease. The etiology of parathyroid carcinoma is unknown, however, the recently discovered HRPT2 gene, a tumor ...
Elizabeth A, Mittendorf +1 more
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AbstractParathyroid carcinoma is an uncommon malignancy. It accounts for less than 1% of cases of primary hyperparathyroidism (HPT). It is manifested by severe hypercalcemia and up to 50% of patients will have concomitant kidney or bone disease. The etiology of parathyroid carcinoma is unknown, however, the recently discovered HRPT2 gene, a tumor ...
Elizabeth A, Mittendorf +1 more
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Current Opinion in Nephrology and Hypertension, 2002
The serum levels of parathyroid hormone and magnesium depend on each other in a complex manner. The secretion of parathyroid hormone by the parathyroid is physiologically controlled by the serum calcium level, but magnesium can exert similar effects. While low levels of magnesium stimulate parathyroid hormone secretion, very low serum concentrations ...
Thorsten, Vetter, Martin J, Lohse
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The serum levels of parathyroid hormone and magnesium depend on each other in a complex manner. The secretion of parathyroid hormone by the parathyroid is physiologically controlled by the serum calcium level, but magnesium can exert similar effects. While low levels of magnesium stimulate parathyroid hormone secretion, very low serum concentrations ...
Thorsten, Vetter, Martin J, Lohse
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PARATHYROID ADENOMA AND HYPERTROPHY OF THE PARATHYROID GLANDS
Journal of the American Medical Association, 1946The clinical recognition of hyperparathyroidism depends on interpretation of its protean manifestations. These have been divided into (1) those symptoms resulting from chemical alterations in the blood, (2) those symptoms resulting from involvement of the urinary tract and (3) those symptoms resulting from involvement of the skeleton.
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Parathyroid Hormone and Parathyroid hormone-Related Protein
The Biomedical & Life Sciences Collection, 2001Publisher Summary This chapter focuses on current understanding of the physiology and mechanism of action of these polypeptides. Parathyroid hormone (PTH) and PTH-related protein (PTHrP) are major factors that regulate skeletal physiology and mineral homeostasis.
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THYROIDECTOMY AND THE PARATHYROIDS
Archives of Surgery, 1948THE RECOGNITION of the parathyroid glands is a challenge to the surgeon. Although the dire consequences of injury to the glands or of removal of the glands are generally appreciated, it is safe to say that thyroidectomies are done without the operator's being able definitely to recognize this tissue.
G A, JOHNSTONE, F, VOTH-OSTENDORPH
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