Focus on parathyroid carcinoma
International Journal of Surgery, 2011 Parathyroid carcinoma is a malignant neoplasm affecting 05-2 per cent of all patients with primary hyperparathyroidism that was first described by de Quevain in 1904. To day it continues to defy diagnosis and treatment. It is difficult to diagnose in part because of its rarity, lack of definitive diagnostic markers and overlapping clinical features of ...
Sven Jonas, Woubet T. Kassahun
openaire +3 more sources
Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin
The FEBS Journal, EarlyView.The secretion of parathyroid hormone (PTH) from the chief cells in the parathyroid glands is regulated by the concentration of extracellular calcium. Epiprofin (Epfn) expression is induced by NFATc2 in response to elevated serum calcium, and Epfn negatively regulates PTH production.
Takashi Nakamura +8 more
wiley +1 more source
A Rare Occurrence of Ectopic Parathyroid Carcinoma Presenting as a Case of Recurrent Fractures [PDF]
, 2023 Ectopic parathyroid tumors are uncommon, accounting for only 6% of parathyroid adenomas, and even fewer cases are attributed to parathyroid carcinomas. While ectopic parathyroid carcinoma in the anterior mediastinum is a rare condition, the occurrence of
Jamal, Aisha +3 more
core +1 more source
Molecular genetics of syndromic and non‐syndromic forms of parathyroid carcinoma
Human Mutation, 2017 Parathyroid carcinoma (PC) may occur as part of a complex hereditary syndrome or an isolated (i.e., non‐syndromic) non‐hereditary (i.e., sporadic) endocrinopathy.
L. Cardoso, M. Stevenson, R. Thakker
semanticscholar +1 more source
A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection [PDF]
, 2020 Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes.
Abbas, Syed Akbar +6 more
core +1 more source
Recent Advances in Diagnostics and Therapeutics for Paediatric Thyroid Cancer
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Purpose of Review Paediatric thyroid cancer management traditionally relied on extrapolation from adult data and, despite good survival outcomes, often involved extensive surgical approaches and radioactive iodine (RAI) therapy with potentially life‐long complications.
Joel A. Vanderniet +9 more
wiley +1 more source
A Precision Diagnostic Framework of Renal Cell Carcinoma on Whole-Slide Images using Deep Learning [PDF]
arXiv, 2021 Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade classification are the fundamental diagnostic indicators for renal cell carcinoma (RCC) in whole-slide images (WSIs). However,
arxiv
Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard [PDF]
, 2018 Purpose: Aim of the study was to: 1) present MDCT characteristics of different mediastinal mass lesions, 2) estimate proportion of benign and malignant mediastinal mass lesions based on MDCT findings, and 3) find out the diagnostic accuracy with ...
Jaipal, Usha +3 more
core +1 more source
Quantitative Imaging in Medicine and Surgery, 2019 Background To investigate the role of 99mTc-labeled sestamibi (99mTc-MIBI) retention level in the assessment of malignant potential of parathyroid lesions.
Min Zhang +8 more
semanticscholar +1 more source
Primary hyperparathyroidism in a domestic shorthair cat following I131 radioiodine therapy
Journal of Small Animal Practice, EarlyView.A 12‐year‐old male neutered domestic shorthaired cat presented for further assessment of a cervical mass, having undergone radioiodine therapy for treatment of hyperthyroidism 2 years prior to presentation. Initial cytological diagnosis of the mass was supportive of a carcinoma and laboratory results were consistent with primary hyperparathyroidism ...
E. Ruane +3 more
wiley +1 more source