Results 51 to 60 of about 634,140 (212)

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Parathyroid carcinoma — a study of 29 cases [PDF]

open access: yes, 2022
Introduction: Parathyroid carcinoma is a rare condition and accounts for < 1% of cases of sporadic primary hyperparathyroidism. It accounts for 0.005% of all cancers.
Buła, Grzegorz; Department of General and Endocrine Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland   +4 more
core   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

open access: yesFlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu   +3 more
wiley   +1 more source

A Rare Constellation of Hürthle Cell Thyroid Carcinoma and Parathyroid Carcinoma [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Separate occurrence of thyroid and parathyroid carcinoma in patients is extremely rare, and to the best of our knowledge, only 7 patients with documented parathyroid and papillary thyroid carcinomas have been described formerly in published reports.
Mehrnoosh Zakerkish   +3 more
doaj   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Postoperative Hypocalcemia Following Total Thyroidectomy Versus Completion Thyroidectomy

open access: yesThe Laryngoscope, EarlyView.
Completion thyroidectomy performed with at least a three‐month interval demonstrates superior parathyroid preservation compared to primary total thyroidectomy, as evidenced by significantly higher postoperative parathyroid hormone levels (51.90 ± 30.26 pg/mL vs. 30.90 ± 17.10 pg/mL, p = 0.006).
Mehmet Turan Cicek   +3 more
wiley   +1 more source

Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature

open access: yesCase Reports in Endocrinology, 2020
Introduction. Parathyroid carcinoma is one of the rarest cancers in normal population, and it is extremely uncommon in the setting of tertiary hyperparathyroidism. Indeed, only 24 cases have been reported in the literature. Presentation of the Case.
Federico Cappellacci   +6 more
doaj   +1 more source

Hemithyroidectomy Eligibility Under ATA 2015 and 2025 Criteria: A Reclassification Cohort Study

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To compare hemithyroidectomy eligibility and completion thyroidectomy recommendations under the ATA 2015 and ATA 2025 criteria within the same patient cohort (primary aim) and, as a secondary descriptive analysis, to assess the concordance between these guideline‐based classifications and the operations actually performed.
Muhammer Ergenç   +3 more
wiley   +1 more source

Synchronous Parathyroid and Papillary Thyroid Carcinoma [PDF]

open access: yes, 2005
Concomitant thyroid disease is not unusual among patients with primary hyperparathyroidism. However, the simultaneous occurrence of parathyroid and thyroid carcinoma is extremely rare.
Lin, Shi-Dou   +5 more
core   +1 more source

An Unusual Simultaneous Existence of Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Case Report and Review of Literature

open access: yesCase Reports in Endocrinology, 2020
Synchronous parathyroid and papillary thyroid carcinoma are extremely rare. To our knowledge, only 15 cases have been reported in the last four decades.
César Ernesto Lam-Chung   +3 more
doaj   +1 more source

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