Results 51 to 60 of about 696,765 (215)

Current concepts in parathyroid carcinoma: a single Centre experience

BMC Endocrine Disorders, 2019
Background Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features that may reliably distinguish ...
Valentina Ferraro, Lucia Ilaria Sgaramella, Giovanna Di Meo, Francesco Paolo Prete, Francesco Logoluso, Francesco Minerva, Marica Noviello, Giuseppina Renzulli, Angela Gurrado, Mario Testini   +9 more
doaj   +1 more source

Utility of 99mTc-Sestamibi SPECT/CT in the Early Localization of Metastatic Parathyroid Carcinoma [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2018
Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and ...
Patrick Earl Fernando, Patricia Bautista
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

A Rare Parathyroid Carcinoma in Young Adult Man: Therapeutic Challenges in Tertiary Hospital with its Limitations

Indonesian Journal of Cancer
Introduction: Parathyroid carcinoma is a rare malignant neoplasm. The symptoms that arise are related to hyperparathyroid conditions, which are clinically difficult to distinguish between benign and malignant disorders.
Rupita Sari Endangena Sitanggang, Yohana Azhar, Hasrayati Agustina   +2 more
doaj   +1 more source

Expression of parathyroid hormone-related protein in gastrointestinal malignancies. [PDF]

, 2006
Parathyroid hormone-related protein (PTHrP) is a peptide hormone which, when abundantly produced by certain tumours, and released into the systemic circulation, stimulates via an endocrine-like pathway, bone resorption and renal calcium reabsorption, by ...
McStay, M.K.G.
core  

The use of cinacalcet hinders the diagnosis of parathyroid carcinoma in a chronic dialysis patient: a case report

BMC Nephrology, 2017
Background Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving chronic dialysis therapy. Although cinacalcet can control parathyroid function and bone turnover, preventing ectopic calcification remains challenging ...
Daisuke Takada, Tatsuo Tsukamoto, Miho Fuse, Shinpei Kada, Motoko Yanagita   +4 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Parathyroid Carcinoma in a Patient With Secondary Hyperparathyroidism and Thyroid Hemiagenesis: A Case Report and Review of the Literature

Ear, Nose & Throat Journal
Parathyroid carcinoma is a rare endocrine tumor. Parathyroid carcinoma in patients with secondary hyperparathyroidism due to chronic kidney disease is also rare. In addition, thyroid hemiagenesis is a rare congenital anomaly.
Shinpei Kada MD, PhD, Miho Tanaka MD, Akihiro Yasoda MD, PhD   +2 more
doaj   +1 more source

Parathyroid Carcinoma, a Rare Entity with Varying Presentation and Treatment

, 2010
Background Parathyroid carcinoma is a rare entity that has diverse presentation and diverse treatments. This case-series highlights the atypical and diverse presentation of parathyroid carcinoma and stresses the importance of the diagnostic approach and ...
Menno R Vriens, Gerlof D Valk, Inne HM Borel Rinkes, Ronald W Ter Haar   +3 more
core   +1 more source

Pathology data set for reporting parathyroid carcinoma and atypical parathyroid neoplasm: recommendations from the International Collaboration on Cancer Reporting. [PDF]

, 2020
Standardized pathologic reporting for cancers improves patient care and prognostic determination. However, access in many countries is limited.
Perrier, Nancy D, Gupta, Ruta, Seethala, Raja R, Williams, Michelle D, DeLellis, Ron A, Natu, Sonali, Johnson, Sarah J, Kameyama, Kaori, Ng, Tony, Perren, Aurel, Gill, Anthony J, Erickson, Lori A, Gupta R, Natu S, DeLellis RA, Erickson LA, Seethala RR, Ng T, Johnson SJ, Gill AJ, Perren A, Williams MD, Perrier ND, Kameyama K   +23 more
core   +1 more source