Results 61 to 70 of about 26,355 (200)

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, EarlyView.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

Parathyroid Carcinoma, a Rare Entity with Varying Presentation and Treatment [PDF]

, 2010
Background Parathyroid carcinoma is a rare entity that has diverse presentation and diverse treatments. This case-series highlights the atypical and diverse presentation of parathyroid carcinoma and stresses the importance of the diagnostic approach and ...
Menno R Vriens, Gerlof D Valk, Inne HM Borel Rinkes, Ronald W Ter Haar   +3 more
core   +1 more source

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, EarlyView.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source

MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10‐Mediated Angiogenesis

Cancer Science, EarlyView.
MEN1 deficiency promotes JunD‐mediated upregulation of MMP10 expression, which cleaves pro‐HB‐EGF and activates endothelial EGFR. This triggers the PI3K/Akt and MEK/ERK signaling pathways, thereby driving angiogenesis and tumor progression. MMP10 inhibitor treatment blocks this cleavage, suppresses EGFR signaling, and thereby delays malignant ...
Chengyu Wei, Xiangyu Liu, Shimin Hu, Xiaodie Shen, Yingli Liu, Xinxin Qin, Ye Zhou, Jianqi Zheng, Bingke Tian, Jingfang Hong, Yongxia Song, Di Wang, Linlin Peng, Jinxia Ding, Fang Wang, Hui Zhang, Shihao Zhang, Huan Qiu   +17 more
wiley   +1 more source

Intrathyroidal parathyroid carcinoma in a pediatric patient [PDF]

, 2011
5 p.Parathyroid carcinoma is unusual and its intrathyroidal variant is extremely rare. Therefore, few cases have been reported to describe a case of parathyroid carcinoma located inside the thyroid gland.
Álvaro Antonio Herrera-Hernández, Julio Alexander Díaz-Pérez, Herrera Hernández, Álvaro Antonio, Herrera, Loren Paola, Loren Paola Herrera, Aranda Valderrama, Paola, Paola Aranda-Valderrama, Diaz Perez, Julio A.   +7 more
core   +1 more source

Optimizing Parathyroid Localization in Real Life: The Role of Expert‐Performed Ultrasonography

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To evaluate the accuracy of expert‐performed ultrasonography (US) for preoperative localization in minimally invasive parathyroidectomy (MIP) compared with community US and other imaging modalities. Study Design Retrospective cohort study. Setting Tertiary referral center for endocrine surgery.
Tzahi Yamin, Nir Battat, Annat Blank, Shmuel Meirsdorf, Bar Sara Zigdon, Oded Cohen, Avi Khafif   +6 more
wiley   +1 more source

Concomitant Hyperparathyroidism Due to Occult Parathyroid Adenoma Detected by Technetium-99m Sestamibi Single-photon Computed Tomography/Computerized Tomography in a Patient with Papillary Thyroid Carcinoma

Journal of Health Science and Medical Research (JHSMR), 2020
Although the occurrence of thyroid and parathyroid diseases is common, concomitant parathyroid adenoma and papillary thyroid carcinoma is rare. We report the case of a 77-year-old Thai woman who was diagnosed to have papillary thyroid carcinoma and ...
Jiraporn Sriprapaporn, Pongthep Pisarnturakit, Tauangtham Anekpuritanang   +2 more
doaj   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Metastatic parathyroid carcinoma in the MEN2A syndrome. [PDF]

, 1997
We report a patient with a metastatic parathyroid carcinoma and medullary carcinoma of the thyroid. This patient represents a variation of the multiple endocrine neoplasia syndrome (MEN) type 2A. There was no evidence of a phaeochromocytoma.
Simmgen, M, Williamson, C, Jenkins, PJ, Thakker, Rajesh, Chew, SL, Britton, K, Satta, MA, Lowe, DG, Thakker, RV, Drake, WM, Besser, GM   +10 more
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source