Results 41 to 50 of about 50,714 (241)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

The Parathyroid Gland: An Overall Review of the Hidden Organ for Radiologists

Journal of the Korean Society of Radiology
Parathyroid glands are small endocrine glands that regulate calcium metabolism by producing parathyroid hormone (PTH). These are located at the back of the thyroid gland.
Suho Kim, Jung Hee Shin, Soo Yeon Hahn, Haejung Kim, Myoung Kyoung Kim   +4 more
doaj   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Nonfunctional parathyroid cyst: case report

São Paulo Medical Journal
CONTEXT: Parathyroid cysts are rare clinical and pathological entities, with less than 300 cases reported. The inferior parathyroid glands are most commonly involved, with left-side predominance.
Carlos Eduardo Molinari Nardi, Ricardo Adriano Nasser Barbosa da Silva, Cynthia Maria Massarico Serafim, Rogério Aparecido Dedivitis   +3 more
doaj   +1 more source

Recurrence hyperparathyroidism caused by synchronous parathyroid carcinoma and parathyromatosis in a patient with long-term hemodialysis

BMC Nephrology, 2023
Background Parathyroid carcinoma and parathyromatosis are very rare diseases in patients on hemodialysis. Its pathogenesis, clinical features, preoperative diagnosis, and surgery are challenging.
Jun Yang, Xili Lu, Pingping Zhou, Hao Liu, Jili Wang, Xinhui Su   +5 more
doaj   +1 more source

The Parathyroid Gland and Heart Disease [PDF]

Methodist DeBakey Cardiovascular Journal, 2017
The parathyroid glands are critical to maintaining calcium homeostasis through actions of parathyroid hormone (PTH). Recent clinical and molecular research has shown that direct and indirect actions of PTH also affect the heart and vasculature through downstream actions of G protein-coupled receptors in the myocardium and endothelial cells.
Spandana J, Brown, Mary D, Ruppe, Laila S, Tabatabai   +2 more
openaire   +2 more sources

Estimating the global prevalence of secondary hyperparathyroidism in patients with chronic kidney disease

Frontiers in Endocrinology
BackgroundChronic kidney disease (CKD)-related secondary hyperparathyroidism (SHPT) is associated with higher morbidity and death. The goal of this study was to mine the SHPT data already available to do a meta-analysis on the global prevalence of SHPT ...
Yichao Wang, Yichao Wang, Jiaye Liu, Jiaye Liu, Yiqiao Fang, Yiqiao Fang, Shengliang Zhou, Shengliang Zhou, Xueting Liu, Zhihui Li, Zhihui Li   +10 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report

Archives of Endocrinology and Metabolism
The concomitant occurrence of primary hyperparathyroidism (PHPT) due to parathyroid adenoma and papillary thyroid carcinoma (PTC) is not common. The co-occurrence of parathyroid tumors and thyroid diseases can lead to misdiagnosis owing to mutual ...
Qing Li, Jiemin Pan, Quanyong Luo, Yan Wang, Yuqian Bao, Weiping Jia   +5 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source