Results 81 to 90 of about 561,799 (392)

Neural Annotation Refinement: Development of a New 3D Dataset for Adrenal Gland Analysis [PDF]

open access: yesarXiv, 2022
The human annotations are imperfect, especially when produced by junior practitioners. Multi-expert consensus is usually regarded as golden standard, while this annotation protocol is too expensive to implement in many real-world projects. In this study, we propose a method to refine human annotation, named Neural Annotation Refinement (NeAR).
arxiv  

PCG-Cut: Graph Driven Segmentation of the Prostate Central Gland [PDF]

open access: yesPLoS ONE 8(10): e76645 (2013), 2013
Prostate cancer is the most abundant cancer in men, with over 200,000 expected new cases and around 28,000 deaths in 2012 in the US alone. In this study, the segmentation results for the prostate central gland (PCG) in MR scans are presented. The aim of this research study is to apply a graph-based algorithm to automated segmentation (i.e. delineation)
arxiv   +1 more source

Evaluation of conventional imaging techniques on preoperative localization in primary hyperparathyroidism [PDF]

open access: yes, 2015
We aimed to evaluate the diagnostic and preoperative localization capacity of Tc-99m methoxyisobutylnitrile (MIBI) parathyroid scintigraphy and ultrasonography (USG) in enlarged parathyroid glands in the primary hyperparathyroidism (pH PT), as well as ...
Demir, Hasan Deniz   +6 more
core  

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

open access: yesAdvanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie   +10 more
wiley   +1 more source

Effect of calcitriol treatment on arterial stiffness in people with type 2 diabetes and stage 3 chronic kidney disease

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 1, Page 279-289, January 2023., 2023
Aims Active vitamin D deficiency is associated with increased aortic‐pulse wave velocity (Ao‐PWV) in people with type 2 diabetes (T2DM) and chronic kidney disease (CKD). There are no randomised controlled trials investigating the effect of active vitamin D treatment on Ao‐PWV in people with T2DM and CKD.
Janaka Karalliedde   +10 more
wiley   +1 more source

Analysis of α-Klotho, Fibroblast Growth Factor-, Vitamin-D and Calcium-Sensing Receptor in 70 Patients with Secondary Hyperparathyroidism

open access: yesKidney & Blood Pressure Research, 2013
Background/Aims: Secondary hyperparathyroidism (sHPT) is known as a very common complication in patients with chronic kidney disease, and G-protein-coupled calcium-sensing receptor (CaSR), Vitamin D receptor (VDR) and Fibroblast growth factor receptor ...
Joerg Latus   +11 more
doaj   +1 more source

Reflections of the Anesthetic Management in a Case of Parathyroid Adenoma: A Case Report

open access: yesArchives of Anesthesia and Critical Care, 2023
Parathyroid adenomas are usually an incidental finding and present more commonly in women. The parathyroid gland releases parathyroid hormone(PTH), which is essential to maintain calcium homeostasis.
Jyoti Deshpande   +2 more
doaj   +1 more source

Identification of signaling pathways in early mammary gland development by mouse genetics [PDF]

open access: yes, 2004
The mammary gland develops as an appendage of the ectoderm. The prenatal stage of mammary development is hormone independent and is regulated by sequential and reciprocal signaling between the epithelium and the mesenchyme.
A Yang   +20 more
core   +2 more sources

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

open access: yesAdvanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi   +8 more
wiley   +1 more source

Gαq signalling from endosomes: A new conundrum

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

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