Results 121 to 130 of about 121,783 (270)
Human diseases caused by homozygous PTH1R mutations
Frontiers in EndocrinologyThe parathyroid hormone receptor type 1 (PTH1R) is a G protein-coupled receptor that mediates the actions of parathyroid hormone (PTH) in the regulation of blood calcium levels, as well as PTH-related protein (PTHrP) in the regulation of skeletal ...
Ignacio Portales-Castillo +4 more
doaj +1 more source
Modulation by cAMP of a Slowly Activating Potassium Channel Expressed in \u3cem\u3eXenopus\u3c/em\u3e Oocytes [PDF]
, 1992 When expressed in the Xenopus oocyte, the minK protein induces a slowly activating voltage-dependent potassium current (Isk). We studied the modulation of this current by altering intracellular cAMP levels and found that the amplitude of Isk is ...
Blumenthal, Edward M +1 more
core +1 more source
Veterinary Surgery, EarlyView.Abstract Objective To describe the procedure and short‐term outcomes of two dogs that underwent laparoscopic stapled partial cystectomy with intraoperative cystoscopy for excision of solitary, non‐trigonal, urothelial carcinoma lesions. Animals A 12‐year‐old female spayed mixed breed and a 13‐year‐old female spayed Siberian Husky.
Maureen A. Griffin +2 more
wiley +1 more source
Parathyroid Hormone-Related Protein/Parathyroid Hormone Receptor 1 Signaling in Cancer and Metastasis. [PDF]
Cancers (Basel), 2023 Zhao Y, Su S, Li X.
europepmc +1 more source
Women in space: A review of known physiological adaptations and health perspectives
Experimental Physiology, EarlyView.Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Hypercalcemia of malignancy and new treatment options
Therapeutics and Clinical Risk Management, 2015 Hillel Sternlicht,1 Ilya G Glezerman1,2 1Division of Nephrology and Hypertension, Weill Cornell Medical College, 2Renal Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA Abstract: Hypercalcemia of malignancy affects up to one in ...
Sternlicht H, Glezerman IG
doaj
The nuclear localization sequence and C-terminus of parathyroid hormone-related protein regulate normal pancreatic islet development and function. [PDF]
Gen Comp Endocrinol, 2023 Max-Harry IM +7 more
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 309-322, June 2026.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Parathyroid hormone related protein (PTHrP) in patients with pancreatic carcinoma and overt signs of disease progression and host tissue wasting. [PDF]
Transl Oncol, 2023 Iresjö BM, Kir S, Lundholm K.
europepmc +1 more source