Results 71 to 80 of about 146,694 (331)

Active vitamin D (1,25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European male aging study (EMAS) [PDF]

, 2013
<p>Context: There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)2D] on bone health including turnover.</p> <p>Objective: The objective of the study was to determine the influence of 1,25(OH ...
Akhter, Aleksander Giwercman, Annesley, Araujo, Bates, Bischoff-Ferrari, Boonen, Boonen, Bouillon, Bouillon, Bouillon, Casetta, Christensen, Cummings, Curtis, David M. Lee, Dirk Vanderschueren, Evelien Gielen, Felipe F. Casanueva, Frank Claessens, Frederick C. W. Wu, Gianni Forti, Gluer, Gyorgy Bartfai, Hannan, Herfarth, Ilpo T. Huhtaniemi, Ivo Jans, Jaak Billen, Jacques, Joseph D. Finn, Judith E. Adams, Kanis, Kate A. Ward, Krzysztof Kula, Kuchuk, Lee, Lee, Lieben, Lips, Lips, Lips, Lips, Lips, Margus Punab, Michael E. J. Lean, Michaël Laurent, Moan, Murphy, Neil Pendleton, Norman, Orwoll, Pye, Quesada, Reid, Reuben, Rudnicki, Saquib, Sherman, Stephen R. Pye, Steven Boonen, Szulc, Terence W. O'Neill, Thang S. Han, Vanderschueren, Vieth, Washburn, Woitge   +67 more
core   +3 more sources

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian, Saharnaz Bargh, Almina Gülerman, Veli Cengiz Özalp, Özcan Erel, Nimet Yildirim‐Tirgil   +5 more
wiley   +1 more source

PARATHYROID HORMONE-RELATED PROTEIN AND PROSTATE CANCER

Кубанский научный медицинский вестник, 2017
The survey presents the existing arguments and facts about the parathyroid hormone-related protein (PTHrP) and its role in pathophysiological and pathobio-chemical mechanisms that are related to onco-transformation of prostate.
V. L. MEDVEDEV, E. A. STRYGINA, A. N. KURZANOV   +2 more
doaj   +1 more source

Biosynthesis of Proparathyroid Hormone and Parathyroid Hormone by Human Parathyroid Glands [PDF]

Journal of Clinical Investigation, 1973
Human parathyroid glands obtained at autopsy were incubated with [(3)H]leucine and [(3)H]lysine. After incubation, nonradioactive parathyroid tissue of either human or bovine origin was added. Radioactive parathyroid hormone and proparathyroid hormone were isolated from the gland and medium by organic solvent and salt fractionation, trichloroacetic ...
David V. Cohn, James W. Hamilton, Paul I. Liu, Luke L. H. Chu, Ronal R. Macgregor   +4 more
openaire   +3 more sources

Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide [PDF]

Cardiovascular Research, 1998
Cardiovascular cells (cardiomyocytes and smooth muscle cells) are target cells for parathyroid hormone (PTH) and the structurally related peptide parathyroid hormone-related peptide (PTH-rP). PTH activates protein kinase C (PKC) of cardiomyocytes via a PKC activating domain previously identified on chondrocytes.
Klaus-Dieter Schlüter, Hans Michael Piper   +1 more
openaire   +3 more sources

The Diagnostic Accuracy of High Resolution Ultrasound Imaging for Detection of Secondary Hyperparathyroidism in Patients with Chronic Renal Failure [PDF]

Ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. This study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. From March
اناری, حسن, بشردوست, بهمن, رفاهی, سهیلا, پورعیسی, مسعود   +3 more
core  

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Hypercalcemia of Malignancy Attributed to Cosecretion of PTH and PTHRP in Lung Adenocarcinoma

AACE Clinical Case Reports, 2021
Introduction: Hypercalcemia of malignancy (HCM) portends a very poor prognosis, and no established guidelines exist regarding its management. Most instances of HCM are due to local osteolysis or secretion of parathyroid hormone related-peptide, while ...
Jeffrey M. Kroopnick, MD, Ubaldo Martinez-Outschoorn, MD, Madalina Tuluc, MD, PhD, Caroline S. Kim, MD   +3 more
doaj  

Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality [PDF]

, 2019
A goal of osteoporosis therapy is to restore lost bone with structurally sound tissue. Mice lacking the transcription factor Nuclear Matrix Protein 4 (Nmp4, Zfp384, Ciz, ZNF384) respond to several classes of osteoporosis drugs with enhanced bone ...
Adaway, Michele, Allen, Matthew R., Bidwell, Joseph P., Brustovetsky, Nickolay, Burr, David B., Childress, Paul J., Hamilton, James, Jacobs, Kylie, Klunk, Angela, Liu, Yunlong, Misra, Jagannath, Mosley, Amber L., Robling, Alexander G., Shao, Yu, Stayrook, Keith R., Vashishth, Deepak, Wallace, Joseph M., Wek, Ronald C., Wichern, Emily   +18 more
core   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source