Bone Remodeling and Modeling: Cellular Targets for Antiresorptive and Anabolic Treatments, Including Approaches Through the Parathyroid Hormone (PTH)/PTH-Related Protein Pathway. [PDF]
Martin TJ, Seeman E.
europepmc +1 more source
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley +1 more source
Parathyroid hormone-related protein (PTH-rP) and the control of the growth and differentiation of normal human keratinocytes. [PDF]
Parathyroid hormone-related protein (PTH-rP) and the control of the growth and differentiation of normal human ...
J. F. WHITFIELD +4 more
core
Cellular Basis for Sequencing of Antiresorptive and Anabolic Therapies for Bone: Commentary on "Bone Remodeling and Modeling: Cellular Targets for Antiresorptive and Anabolic Treatments, Including Approaches Through the Parathyroid Hormone (PTH)/PTH-Related Protein Pathway". [PDF]
Sims NA.
europepmc +1 more source
Vitamin D Supplementation to Prevent Post‐Thyroidectomy Hypocalcemia
ABSTRACT Objective Hypocalcemia is the most common complication following thyroidectomy. Previous studies yielded inconsistent results on whether vitamin D3 prevents postoperative hypocalcemia and were conducted in non‐European countries with different dietary habits and baseline vitamin D levels.
Jeresa I. A. Willems +9 more
wiley +1 more source
Parathyroid Adenoma: is Sestamibi scintigraphy mandatory? [PDF]
Localization of parathyroid adenoma using 99mTc scintigraphy is the standard of care. However, of late, ultrasound has been employed to this end with increasing frequency.1, 2, 3 The employment of intra-operative PTH estimation (IOPTH) has further ...
Vedachalam, Sucharitha; Madras Medical College +1 more
core +1 more source
ABSTRACT Aims Despite the known association between abdominal obesity (AO) and vitamin D deficiency, it remains unclear whether this combination is associated with higher mortality risk. We investigated whether the coexistence of AO and vitamin D deficiency elevates the risk of death.
Joyce da Silva Milliati +7 more
wiley +1 more source
Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks. [PDF]
Rendina-Ruedy E, Rosen CJ.
europepmc +1 more source
ABSTRACT Aims While being recognised for stimulating pancreatic insulin secretion, GIP and GLP‐1 exert various extrapancreatic effects relevant in the context of incretin‐based therapies. Here, we evaluated the extrapancreatic effects of GIP and GLP‐1, separately and combined, on postprandial physiology in totally pancreatectomised individuals ...
Liva S. L. Krogh +8 more
wiley +1 more source
Diagnosis and therapy of parathyroid cysts: A review of 7 cases
Parathyroid cysts (PC) are relatively rare lesions in the neck. This study aims to present 7 new cases of PC and share our experience. Between September 2017 and December 2022, seven patients diagnosed with PCs underwent surgery.
Zhiwei Zhou, Jingjia Li, Weixiong Chen
doaj +1 more source

