Results 181 to 190 of about 57,490 (237)
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Parathyroid Hormone (PTH) Suppresses Rat PTH/PTH-Related Protein Receptor Gene Promoter
Biochemical and Biophysical Research Communications, 2001Parathyroid hormone (PTH) regulates osteoblasts via a G protein-linked PTH/PTH-related protein (PTHrP) receptor. PTH effects on PTH/PTHrP receptor gene expression were studied in UMR 106 osteoblast-like cells. In heterogeneous nuclear RNA and Northern analysis, PTH suppressed PTH/PTHrP receptor transcription.
Noboru Horiuchi, T Kawane, N Horiuchi
exaly +3 more sources
Conformational studies of parathyroid hormone (PTH)/PTH-related protein (PTHrp) chimeric peptides
Biopolymers, 2000The N-terminal 1-34 segments of both parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) bind and activate the same membrane-embedded G protein-coupled receptor (PTH1 Rc) present on the surface of cells in target tissues such as bone and kidney.
Elisabetta Schievano +2 more
exaly +3 more sources
Cisandtransacting factors in the regulation of parathyroid hormone (PTH) mRNA stability by calcium and phosphate [PDF]
FEBS Letters, 2002 Calcium and phosphate regulate parathyroid hormone (PTH) mRNA stability through differences in binding of parathyroid proteins to an element in its 3′-untranslated region. One of the proteins is AUF1 (A+U-rich element binding factor 1).
Tally Naveh-Many
exaly +2 more sources
The parathyroid glands and parathyroid hormone: Insights from PTH gene mutations
2022Nine mutations have been discovered in the parathyroid hormone (PTH) gene since it was initially sequenced in 1983. An autosomal dominant C18R mutation in the signal peptide was first reported in 1990, followed by an exon skipping mutation, leading to loss of exon 2 in 1992; the latter mutation prevents PTH biosynthesis, as exon 2 contains the ...
Joon-Hyop, Lee, Sihoon, Lee
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Parathyroid Hormone-Related Peptide (PTHrP) and Parathyroid Hormone (PTH)/PTHrP Receptor
Critical Reviews™ in Eukaryotic Gene Expression, 1998Parathyroid hormone-related peptide (PTHrP) has been identified as the factor responsible for the humoral hypercalcemia of malignancy (HHM). Since the cloning of the cDNA, it has become clear that PTHrP is a prohormone that is posttranslationally cleaved to yield a complex family of peptides.
B, Lanske, H M, Kronenberg
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Vascular Effects of Parathyroid Hormone (PTH)
1982PTH causes dose dependent transient vasodilatation in various vascular beds, specifically renal, coeliac, coronary, but not osseous. It has an acute dose-dependent hypotensive effect in the intact animal which is not mediated by alpha- or beta-adrenergic, cholinergic or histaminergic mechanisms.
M, Rambausek +6 more
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