Results 191 to 200 of about 57,490 (237)
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Endocrinology, 1988
Human PTH (hPTH)-(3-84) and hPTH-(8-84) were synthesized in Escherichia (E.) coli when the cells were transformed with a multicopy plasmid in which the transcription of human preproPTH cDNA is directed by the E. coli lac promoter. PTH fragments were extracted from cells and purified by reverse phase HPLC.
W, Born +5 more
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Human PTH (hPTH)-(3-84) and hPTH-(8-84) were synthesized in Escherichia (E.) coli when the cells were transformed with a multicopy plasmid in which the transcription of human preproPTH cDNA is directed by the E. coli lac promoter. PTH fragments were extracted from cells and purified by reverse phase HPLC.
W, Born +5 more
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Endocrinology, 1994
The PTH/PTH-related peptide receptor is a member of a newly discovered family of G-protein-coupled receptors. Strikingly conserved features among these receptors include the positioning of eight extracellular cysteines and several other residues that are located predominantly within the membrane-embedded region. Deletion mutants or receptors with point
C, Lee +7 more
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The PTH/PTH-related peptide receptor is a member of a newly discovered family of G-protein-coupled receptors. Strikingly conserved features among these receptors include the positioning of eight extracellular cysteines and several other residues that are located predominantly within the membrane-embedded region. Deletion mutants or receptors with point
C, Lee +7 more
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The Journal of Clinical Endocrinology & Metabolism, 1988
Most studies of circulating PTH levels using traditional RIAs have supported the concept of physiological hyperparathyroidism of pregnancy, with pregnant women having serum immunoreactive PTH levels significantly higher than those in nonpregnant subjects.
O K, Davis +5 more
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Most studies of circulating PTH levels using traditional RIAs have supported the concept of physiological hyperparathyroidism of pregnancy, with pregnant women having serum immunoreactive PTH levels significantly higher than those in nonpregnant subjects.
O K, Davis +5 more
openaire +2 more sources
Biopolymers, 1999
The N-terminal 1-34 segments of both parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) bind and activate the same membrane receptor in spite of major differences between the two hormones in their amino acid sequence. Recently, it was shown that in (1-34)PTH/PTHrP segmental hybrid peptides, the N-terminal 1-14 segment of PTHrP is
PEGGION, EVARISTO +5 more
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The N-terminal 1-34 segments of both parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) bind and activate the same membrane receptor in spite of major differences between the two hormones in their amino acid sequence. Recently, it was shown that in (1-34)PTH/PTHrP segmental hybrid peptides, the N-terminal 1-14 segment of PTHrP is
PEGGION, EVARISTO +5 more
openaire +3 more sources
Metabolism of Parathyroid Hormone and Interpretation of Radioimmunoassays for PTH
1985With the development of radioimmunoassays that are specific for certain regions of the parathyroid hormone (PTH) molecule, the fate of PTH that is secreted into the circulating blood has been partially clarified.
Eduardo Slatopolsky +3 more
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Endocrinology, 1992
Hypertension is often accompanied by abnormalities of calcium homeostasis, including hyperparathyroidism with reduced target organ responses to PTH in kidney and bone. Due to this association between PTH and hypertension and since PTH and the paracrine factor PTH-related protein (PTHrp) have both been shown to exert marked changes in cardiovascular ...
D J, DiPette +3 more
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Hypertension is often accompanied by abnormalities of calcium homeostasis, including hyperparathyroidism with reduced target organ responses to PTH in kidney and bone. Due to this association between PTH and hypertension and since PTH and the paracrine factor PTH-related protein (PTHrp) have both been shown to exert marked changes in cardiovascular ...
D J, DiPette +3 more
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Parathyroid Hormone (PTH) Assay of Parathyroid Cysts Examined by Fine-Needle Aspiration Biopsy
American Journal of Clinical Pathology, 1986The authors report three cases of parathyroid cysts examined by the fine-needle aspiration biopsy technic. A presumptive diagnosis of parathyroid cyst was made when characteristic water-clear fluid was aspirated. The diagnosis was then confirmed by parathyroid hormone (PTH) assay. The authors believe that the C-terminal/midmolecule determination should
J F, Silverman +3 more
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The Effects of Parathyroid Hormone (PTH) on Ca Transport
1991Parathyroid hormone (PTH) stimulates active Ca2+ reabsorption in the distal convoluted tubule of the rat and in the cortical connecting tubule, distal convoluted tubule, and granular portion of the cortical collecting tubule of the rabbit. The dominant mechanism of Ca2+ reabsorption in the proximal tubules is passive diffusion via the paracellular ...
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[Roles of parathyroid hormone (PTH) on phosphate metabolism].
Clinical calcium, 2005Changes in the extracellular concentration of inorganic phosphate (Pi) modulate cellular function in a physiologically relevant manner. High serum Pi leads to an increase in PTH secretion, PTH mRNA stability, and parathyroid cell (PT) proliferation.
Mikiko, Ito +2 more
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[Compounds modulating parathyroid hormone (PTH) secretion].
Clinical calcium, 2005The control of parathyroid hormone (PTH) secretion is strictly regulated by the parathyroid Ca receptor (CaR). Calcimimetics and calcilytics selectively act on the parathyroid CaR to inhibit and enhance PTH secretion, respectively. According to the recent pharmacological two-state model, calcimimetics act on the CaR as allosteric agonists to stabilize ...
N, Nagano, H, Iijima
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