Results 1 to 10 of about 16,021 (201)
Somatostatin receptor expression in parathyroid neoplasms. [PDF]
Endocr Connect, 2019 Introduction Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging. The diagnostic criteria for parathyroid carcinoma are local and/or metastatic spreading.
Storvall S +6 more
europepmc +8 more sources
Reticular fibre structure in the differential diagnosis of parathyroid neoplasms. [PDF]
Diagn Pathol, 2023 Abstract Background To investigate the characteristics of reticular fibre structure (RFS) in parathyroid adenoma (PTA), atypical parathyroid tumour (APT), and parathyroid carcinoma (PTC), and to assess its value as a diagnostic indicator.
Hu X +10 more
europepmc +4 more sources
Mathematical model for preoperative differential diagnosis for the parathyroid neoplasms. [PDF]
J Pathol Inform, 2022 Preoperative diagnosis of parathyroid carcinoma (PC) is critical for the determination of the scope of surgical intervention. Nowadays, specific diagnostic markers for differentiation of PC and benign tumors are unknown, and less than half of patients with PC undergo necessary en bloc surgery.
Krupinova JA +11 more
europepmc +5 more sources
Genetic and Epigenetic Alterations in Parathyroid Neoplasms. [PDF]
Iran J Pathol, 2022 The exact etiology of parathyroid carcinomas (PC) is still unknown. Their associations have with several inherited syndromes or specific genetic lesions have been established. The management of PC is challenging for clinicians. The complexity of molecular phenotypes increases with tumor aggressiveness.
Miratashi Yazdi SA, Nazar E.
europepmc +3 more sources
Novel PRUNE2 Germline Mutations in Aggressive and Benign Parathyroid Neoplasms. [PDF]
Cancers (Basel), 2023 Parathyroid tumors are mostly sporadic but can also occur in familial forms, including different kinds of genetic syndromes with varying phenotypes and penetrance. Recently, somatic mutations of the tumor suppressor gene PRUNE2 were found to be frequent in parathyroid cancer (PC).
Storvall S +3 more
europepmc +3 more sources
Clinical and molecular genetics of parathyroid neoplasms. [PDF]
Best Pract Res Clin Endocrinol Metab, 2010 Primary hyperparathyroidism (HPT) results from the excessive secretion of parathyroid hormone from parathyroid tumours. While most HPT is sporadic, it is associated with a familial syndrome in a minority of cases. The study of these syndromes has helped define the pathophysiology of both familial and sporadic parathyroid neoplasms.
Sharretts JM, Simonds WF.
europepmc +5 more sources
Parathyroid tumors: Molecular signatures [PDF]
, 2021 Parathyroid tumors are rare endocrine neoplasms affecting 0.1–0.3% of the general population, including benign parathyroid adenomas (PAs; about 98% of cases), intermediate atypical parathyroid adenomas (aPAs; 1.2–1.3% of cases) and malignant metastatic ...
Brandi, M. L. +3 more
core +1 more source
Malignant neoplasms and parathyroid adenoma [PDF]
Cancer, 1971 Isolated publications note the association of thyroid carcinoma, thymoma, and parathyroid adenoma with malignancies of other organs or systems. Of 166 patients with histologically proven parathyroid adenomas, 42% of those found at autopsy and 16% of such patients with parathyroidectomy and no autopsy had such malignancies. Seventy-five similar patients
Alfred D. Katz +3 more
openaire +3 more sources
Recent Advances and the Potential for Clinical Use of Autofluorescence Detection of Extra-Ophthalmic Tissues [PDF]
, 2020 The autofluorescence (AF) characteristics of endogenous fluorophores allow the label-free assessment and visualization of cells and tissues of the human body.
Aigner, Felix +7 more
core +1 more source
IMMUNOCHEMICAL IDENTIFICATION OF PARATHYROID HORMONE IN NON-PARATHYROID NEOPLASMS ASSOCIATED WITH HYPERCALCEMIA [PDF]
The Journal of Experimental Medicine, 1964 1. Immunochemical cross-reactivity, but not identity, has been demonstrated between bovine parathyroid hormone and an antigen in biologically active extracts of human parathyroid tissue by quantitative C' fixation and C' fixation inhibition. 2.
Paul L. Munson +2 more
openaire +3 more sources