Results 1 to 10 of about 380,187 (260)

Reticular fibre structure in the differential diagnosis of parathyroid neoplasms [PDF]

Diagnostic Pathology, 2023
Background To investigate the characteristics of reticular fibre structure (RFS) in parathyroid adenoma (PTA), atypical parathyroid tumour (APT), and parathyroid carcinoma (PTC), and to assess its value as a diagnostic indicator.
Xiumei Hu, Shurong He, Xingran Jiang, Ping Wei, Xiang Zhou, Zhongyue Shi, Xue Li, Jun Lu, Hongying Zhao, Bojun Wei, Mulan Jin   +10 more
doaj   +9 more sources

Somatostatin receptor expression in parathyroid neoplasms [PDF]

Endocrine Connections, 2019
Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall, Helena Leijon, Eeva Ryhänen, Johanna Louhimo, Caj Haglund, Camilla Schalin-Jäntti, Johanna Arola   +6 more
doaj   +9 more sources

Mathematical model for preoperative differential diagnosis for the parathyroid neoplasms [PDF]

Journal of Pathology Informatics, 2022
Background and objective: Preoperative diagnosis of parathyroid carcinoma (PC) is critical for the determination of the scope of surgical intervention.
Julia A. Krupinova, Alina R. Elfimova, Olga Yu. Rebrova, Iya A. Voronkova, Anna K. Eremkina, Elena V. Kovaleva, Irina S. Maganeva, Anna M. Gorbacheva, Ekaterina E. Bibik, Andrey A. Deviatkin, Galina A. Melnichenko, Natalia G. Mokrysheva   +11 more
doaj   +6 more sources

Genetic and Epigenetic Alterations in Parathyroid Neoplasms. [PDF]

Iran J Pathol, 2022
The exact etiology of parathyroid carcinomas (PC) is still unknown. Their associations have with several inherited syndromes or specific genetic lesions have been established. The management of PC is challenging for clinicians. The complexity of molecular phenotypes increases with tumor aggressiveness.
Miratashi Yazdi SA, Nazar E.
europepmc   +6 more sources

Novel PRUNE2 Germline Mutations in Aggressive and Benign Parathyroid Neoplasms. [PDF]

Cancers (Basel), 2023
Parathyroid tumors are mostly sporadic but can also occur in familial forms, including different kinds of genetic syndromes with varying phenotypes and penetrance. Recently, somatic mutations of the tumor suppressor gene PRUNE2 were found to be frequent in parathyroid cancer (PC).
Storvall S, Ryhänen E, Karhu A, Schalin-Jäntti C.   +3 more
europepmc   +6 more sources

Primary exploration of cell-free DNA in the plasma of patients with parathyroid neoplasms using next-generation sequencing [PDF]

Cancer Cell International
Background and aims Plasma cell-free DNA (cfDNA) has been used to monitor gene mutations and diagnose tumors. Discriminating parathyroid carcinoma (PC) from parathyroid adenoma (PA) before surgery is difficult because of the overlap in clinical features ...
Qingyuan Zheng, Ming Cui, Ou Wang, Xiaoyan Chang, Jinheng Xiao, Tianqi Chen, Mengyi Wang, Surong Hua, Ya Hu, Quan Liao   +9 more
doaj   +4 more sources

Parathyroid Retrospective Analysis of Neoplasms Incidence (pTRANI Study): An Italian Multicenter Study on Parathyroid Carcinoma and Atypical Parathyroid Tumour [PDF]

Journal of Clinical Medicine, 2023
Background: Parathyroid cancer (PC) is a rare sporadic or hereditary malignancy whose histologic features were redefined with the 2022 WHO classification. A total of 24 Italian institutions designed this multicenter study to specify PC incidence, describe its clinical, functional, and imaging characteristics and improve its differentiation from the ...
Angela Gurrado, Alessandro Pasculli, Nicola Avenia, Rocco Bellantone, Marco Boniardi, Isabella Merante Boschin, Pietro Giorgio Calò, Michele Camandona, Giuseppe Cavallaro, Fabio Cianchi, Giovanni Conzo, Vito D’Andrea, Carmela De Crea, Loredana De Pasquale, Paolo Del Rio, Giovanna Di Meo, Gianlorenzo Dionigi, Chiara Dobrinja, Giovanni Docimo, Fausto Famà, Attilio Galimberti, Luciano Giacomelli, Giuseppa Graceffa, Maurizio Iacobone, Nadia Innaro, Celestino Pio Lombardi, Gabriele Materazzi, Fabio Medas, Barbara Mullineris, Luigi Oragano, N Palestini, Giuliano Perigli, Angela Pezzolla, Francesco Paolo Prete, Marco Raffaelli, Giuseppina Renzulli, L Rosato, Grégorio Scerrino, Lucia Ilaria Sgaramella, Salvatore Sorrenti, Carlotta Testini, Massimiliano Veroux, Guido Gasparri, Mario Testini, pTRANI Study Group   +44 more
core   +10 more sources

Clinical and molecular genetics of parathyroid neoplasms. [PDF]

Best Pract Res Clin Endocrinol Metab, 2010
Primary hyperparathyroidism (HPT) results from the excessive secretion of parathyroid hormone from parathyroid tumours. While most HPT is sporadic, it is associated with a familial syndrome in a minority of cases. The study of these syndromes has helped define the pathophysiology of both familial and sporadic parathyroid neoplasms.
Sharretts JM, Simonds WF.
europepmc   +7 more sources

Prevalence of Parathyroid Carcinoma and Atypical Parathyroid Neoplasms in 153 Patients With Multiple Endocrine Neoplasia Type 1: Case Series and Literature Review. [PDF]

Front Endocrinol (Lausanne), 2020
Purpose: The occurrence of parathyroid carcinoma (PC) and atypical parathyroid neoplasm (APN) in multiple endocrine neoplasia type 1 (MEN1) is rare. The present paper reports the cases of 3 MEN1-PC/APN patients at our center and discusses the prevalence ...
Song A, Yang Y, Liu S, Nie M, Jiang Y, Li M, Xia W, Wang O, Xing X.   +8 more
europepmc   +4 more sources

Shear wave elastography for differentiating parathyroid neoplasms with malignant diagnosis or uncertain malignant potential from parathyroid adenomas: initial experience. [PDF]

Cancer Imaging, 2022
Objective Parathyroid carcinoma (PC) and atypical parathyroid tumor (APT) are rare parathyroid disorders carrying the risk of recurrence of varying degrees. This study aims to explore the value of 2D-shear wave elastography (SWE) in the discrimination of
Liu R, Gao L, Shi X, Ma L, Wang O, Xia W, Hu Y, Xia Y, Jiang Y.   +8 more
europepmc   +4 more sources