Results 1 to 10 of about 20,678 (207)

Somatostatin receptor expression in parathyroid neoplasms [PDF]

Endocrine Connections, 2019
Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall, Helena Leijon, Eeva Ryhänen, Johanna Louhimo, Caj Haglund, Camilla Schalin-Jäntti, Johanna Arola   +6 more
doaj   +6 more sources

Genetic and Epigenetic Alterations in Parathyroid Neoplasms. [PDF]

Iran J Pathol, 2022
The exact etiology of parathyroid carcinomas (PC) is still unknown. Their associations have with several inherited syndromes or specific genetic lesions have been established. The management of PC is challenging for clinicians. The complexity of molecular phenotypes increases with tumor aggressiveness.
Miratashi Yazdi SA, Nazar E.
europepmc   +3 more sources

Mathematical model for preoperative differential diagnosis for the parathyroid neoplasms [PDF]

Journal of Pathology Informatics, 2022
Background and objective: Preoperative diagnosis of parathyroid carcinoma (PC) is critical for the determination of the scope of surgical intervention.
Julia A. Krupinova, Alina R. Elfimova, Olga Yu. Rebrova, Iya A. Voronkova, Anna K. Eremkina, Elena V. Kovaleva, Irina S. Maganeva, Anna M. Gorbacheva, Ekaterina E. Bibik, Andrey A. Deviatkin, Galina A. Melnichenko, Natalia G. Mokrysheva   +11 more
doaj   +2 more sources

Primary exploration of cell-free DNA in the plasma of patients with parathyroid neoplasms using next-generation sequencing [PDF]

Cancer Cell International
Background and aims Plasma cell-free DNA (cfDNA) has been used to monitor gene mutations and diagnose tumors. Discriminating parathyroid carcinoma (PC) from parathyroid adenoma (PA) before surgery is difficult because of the overlap in clinical features ...
Qingyuan Zheng, Ming Cui, Ou Wang, Xiaoyan Chang, Jinheng Xiao, Tianqi Chen, Mengyi Wang, Surong Hua, Ya Hu, Quan Liao   +9 more
doaj   +2 more sources

Reticular fibre structure in the differential diagnosis of parathyroid neoplasms [PDF]

Diagnostic Pathology, 2023
Background To investigate the characteristics of reticular fibre structure (RFS) in parathyroid adenoma (PTA), atypical parathyroid tumour (APT), and parathyroid carcinoma (PTC), and to assess its value as a diagnostic indicator.
Xiumei Hu, Shurong He, Xingran Jiang, Ping Wei, Xiang Zhou, Zhongyue Shi, Xue Li, Jun Lu, Hongying Zhao, Bojun Wei, Mulan Jin   +10 more
doaj   +2 more sources

Parathyroid adenoma masquerading as oncocytic thyroid follicular neoplasm [PDF]

Proceedings of Singapore Healthcare, 2017
Differentiation of thyroid follicular lesions from parathyroid lesions on fine needle aspiration cytology can be very challenging, both being endocrine lesions with overlap in cytomorphologic features. In some cases, it may be impossible to differentiate
Shing Lih Wong, Norman Hok Ling Chan
doaj   +2 more sources

Current Knowledge on Atypical Parathyroid Tumors and Emerging Strategies for Risk Stratification [PDF]

Endocrinology and Metabolism
Atypical parathyroid tumors (APTs) are an uncommon subset of parathyroid neoplasms that carry substantial clinical relevance because of their histological and clinical resemblance to parathyroid cancer.
Hye-Sun Park, Milim Kim, Jong Ju Jeong, Namki Hong, Yumie Rhee   +4 more
doaj   +2 more sources

Glycomic profiling of parathyroid neoplasms via lectin microarray analysis. [PDF]

Endocrine
Parathyroid carcinoma (PC) is a rare malignancy with a poor prognosis. Diagnosis of PC is often difficult in clinical practice and efficient diagnostic markers are still needed for differential diagnosis. Aberrant glycosylations of glycoproteins were identified with lectin microarray in various cancers, while relevant information is lacking in PC.In ...
Zheng Q, Cui M, Xiao J, Yang S, Chen T, Shi Y, Hu Y, Liao Q.   +7 more
europepmc   +3 more sources

Clinical and molecular genetics of parathyroid neoplasms. [PDF]

Best Pract Res Clin Endocrinol Metab, 2010
Primary hyperparathyroidism (HPT) results from the excessive secretion of parathyroid hormone from parathyroid tumours. While most HPT is sporadic, it is associated with a familial syndrome in a minority of cases. The study of these syndromes has helped define the pathophysiology of both familial and sporadic parathyroid neoplasms.
Sharretts JM, Simonds WF.
europepmc   +4 more sources

Maxillary Brown Tumor Unveiling Primary Hyperparathyroidism: A Rare Diagnostic Challenge [PDF]

Clinical Case Reports
Maxillary brown tumors are rare and may mimic malignant or odontogenic lesions, posing a diagnostic challenge. This case highlights that isolated facial swelling may be the first manifestation of primary hyperparathyroidism and underscores the importance
Abdur Rehman, Haitham Akaash, Javeria Awan, Sundas Masood, Rahmat Gul Omarzai   +4 more
doaj   +2 more sources