Results 91 to 100 of about 21,463 (235)

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, EarlyView.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

Cholangiocarcinoma, renal cell carcinoma and parathyroid adenoma found synchronously in a patient on long‐term methotrexate [PDF]

, 2006
Cases of patients developing lymphoma and cutaneous neoplasms after long‐term methotrexate therapy are well documented in the literature; however, there are no reported cases of other neoplasms resulting from methotrexate therapy. A 52‐year‐old woman who
Levy, B.F., Nisar, A., Karanjia, N.D.
core   +1 more source

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, EarlyView.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source

Molecular pathogenesis of parathyroid neoplasia [PDF]

, 2006
Primary hyperparathyroidism commonly results from a benign adenoma of the parathyroid gland and rarely from malignant parathyroid carcinomas, but the two neoplasms can be difficult to distinguish in patients lacking distant metastases.
Shattuck, Trisha Miller
core  

Expression of TRAIL and Fas in Primary Hyperparathyroidism

Journal of Investigative Surgery, 2017
Aim: Differentiating between parathyroid lesions is still difficult and ambiguous. In cases of primary hyperparathyroidism, appropriate and prompt diagnosis is of great importance for effective treatment and follow-up.
Oliwia Anna Segiet, Mariusz Deska, Łukasz Mielańczyk, Marlena Brzozowa-Zasada, Grzegorz Buła, Jacek Gawrychowski, Romuald Wojnicz   +6 more
doaj   +1 more source

MEN1 Deficiency Drives Lung Cancer Progression via Activation of MMP10‐Mediated Angiogenesis

Cancer Science, EarlyView.
MEN1 deficiency promotes JunD‐mediated upregulation of MMP10 expression, which cleaves pro‐HB‐EGF and activates endothelial EGFR. This triggers the PI3K/Akt and MEK/ERK signaling pathways, thereby driving angiogenesis and tumor progression. MMP10 inhibitor treatment blocks this cleavage, suppresses EGFR signaling, and thereby delays malignant ...
Chengyu Wei, Xiangyu Liu, Shimin Hu, Xiaodie Shen, Yingli Liu, Xinxin Qin, Ye Zhou, Jianqi Zheng, Bingke Tian, Jingfang Hong, Yongxia Song, Di Wang, Linlin Peng, Jinxia Ding, Fang Wang, Hui Zhang, Shihao Zhang, Huan Qiu   +17 more
wiley   +1 more source

Galectin-3 expression in parathyroid carcinoma: immunohistochemical study of 26 cases [PDF]

, 2005
The diagnosis of parathyroid carcinoma (PC) is difficult and based on morphological features that are not totally reliable. Several molecular markers proved useful in the evaluation of PC, but their sensitivity, specificity, or both are rather low.
Bussolati, Giovanni, Papotti, Mauro Giulio, Sacerdote, Carlotta, Gasparri, Guido, Bergero, Nicoletta, Volante, Marco, DE POMPA R   +6 more
core   +1 more source

Effect of Medication Intake on Dental Implant‐Related Outcomes—A Scoping Review

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. Material and Methods Electronic and manual searches were conducted for this scoping review.
Alberto Monje, Maria Costanza Soldini, Emilio Couso‐Queiruga, Álvaro Babiano, Vivianne Chappuis   +4 more
wiley   +1 more source

Adjustable Vocal Implant System (VOIS) for Unilateral Vocal Fold Paralysis: Short‐Term Outcomes From a 12‐Patient Case Series

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Unilateral vocal cord palsy (UVCP) significantly affects phonation and swallowing. While injection laryngoplasty and medialisation thyroplasty are effective, both may require revision. Vocal Implant System (VOIS; APrevent Biotech GmbH) is an adjustable titanium‐silicone thyroplasty implant that allows postoperative modification ...
Sam Kebbe, Michael Keane, Chuanyu Gao, Yadsan Devabalan, Guan‐Min Ho, Rohan Bidaye   +5 more
wiley   +1 more source

Large parathyroid adenomas: Potential mechanisms to reconcile adenoma size and disease phenotype [PDF]

, 2023
Parathyroid adenomas weighing more than 3.5 g are reported variously as atypical , large or giant parathyroid adenomas. All such adenomas are rare variants accounting for no more than 1.5% of all parathyroid adenomas.
Bhadada, Sanjay Kumar, Rao, Sudhaker D, Qiu, Shi-Jing, Cook, Bernard C, Bhan, Arti, Pal, Rimesh, Athimulam, Shobana, Kumari, Poonam   +7 more
core   +1 more source