Results 131 to 140 of about 21,377 (235)

Immunohistochemical investigation of angiogenic factors in parathyroid proliferative lesions

, 2006
Objective: The pathological distinction between parathyroid neoplasms and hyperplasias remains difficult in several cases. Endoglin (CD105) is a proliferation-associated and hypoxia-inducible protein abundantly expressed in angiogenic endothelial cells ...
Lazaris, A.C., Brousalis, T., Patsouris, E.S., Papathomas, T., Agrogiannis, G., Thomopoulou, G., Tseleni-Balafouta, S.   +6 more
core  

Aberrant promoter methylation, expression and function of RASSF1A gene in a series of Italian parathyroid tumors [PDF]

Purpose: Aberrant epigenetic features are key events involved in parathyroid tumorigenesis, including DNA methylation, histone methylation, and non-coding RNAs. Ras Association Domain Family Protein1 Isoform A (RASSF1A) and Adenomatous Polyposis of Colon
Tavanti, Giulia Stefania, Morotti, Annamaria, Cetani, Filomena, Fabrizio, Federico Pio, Perticone, Francesca, Carrara, Silvia, Muscarella, Lucia Anna, Maggiore, Riccardo, Guarnieri, Vito, Corbetta, Sabrina, Verdelli, Chiara, Scillitani, Alfredo, Maroni, Paola, Vaira, Valentina   +13 more
core   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only

Organ Medicine, Volume 3, Issue 2, Page 119-124, June 2026.
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai, Yuanyue Guan, Shiwei Cui, Yuan Gao, Zhipeng Zhao, Rui Li, Li Song, Xiuying Zhao, Runqing Li   +8 more
wiley   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, Volume 7, Issue 3, June 2026.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Robotic‐Assisted Transaxillary Parathyroidectomy: A Safe and Cosmetically Alternative for Primary Hyperparathyroidism

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 346-352, June 2026.
ABSTRACT Purpose This study aimed to describe the initial experience with robot‐assisted transaxillary parathyroidectomy (RATP) and to investigate its safety and efficacy as a surgical approach for the treatment of primary hyperparathyroidism (PHPT).
Xi‐Jun Lin, Ping Han, Ren‐Hui Chen, Pei‐Liang Lin, Jing‐Yi Wang, Xiang‐Wei Kong, Fa‐Ya Liang, Xiao‐Ming Huang   +7 more
wiley   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo, James A. Ward, Said Ismael Ng'ang'a, Laurent A. F. Frantz, John A. Browne, Michael Salter‐Townshend, Grace M. O'Gorman, Kieran G. Meade, Emmeline W. Hill, Thomas J. Hall, David E. MacHugh   +10 more
wiley   +1 more source

Dietary management of normoalbuminaemic canine chronic enteropathies

Journal of Small Animal Practice, Volume 67, Issue 6, Page 492-503, June 2026.
Dietary management represents the cornerstone of treatment for chronic enteropathy in dogs, with approximately 50% of cases in referral practice responding to dietary intervention alone. Success rates improve significantly when multiple systematic diet trials are implemented.
A. Kathrani, K. Allenspach, D. Dito, J. Hernandez, S. Unterer, M. Vecchio, C. Webb, M. K. Tolbert   +7 more
wiley   +1 more source

Advances in Visualizing Cytosine Methylation and Allele‐Specific Epigenetic States in Tissue Context

Pathology International, Volume 76, Issue 6, June 2026.
The ICON method enables sequence‐specific, bisulfite‐free visualization of DNA methylation through chemical recognition of methylated cytosines. Following probe hybridization under mild denaturing conditions, methylation‐dependent interstrand complexes are stabilized by covalent crosslinking.
Sohei Kitazawa, Ryuma Haraguchi, Riko Kitazawa   +2 more
wiley   +1 more source