Results 131 to 140 of about 21,463 (235)

The Challenge of Determining the Etiology of Encephalopathy in an Elderly Patient

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Encephalopathy is a heterogeneous clinical syndrome with numerous neurological and systemic etiologies. We report the case of a 67‐year‐old man, a chronic ethanol consumer, admitted with a one‐week history of confusional syndrome. Initial laboratory tests revealed severe hypercalcemia, acute kidney injury, mild anemia, and hyperproteinemia ...
Vlad Alexandru Ionescu   +9 more
wiley   +1 more source

Genomic screening for parathyroid tumor suppressor gene and candidate gene analysis [PDF]

open access: yes, 2006
The molecular pathogenesis of parathyroid adenomas has yet to be fully elucidated with only two genes, cyclin D1 and MENI , established as direct contributors to the pathogenesis of sporadic parathyroid adenomas.
Samander, Elizabeth Hanna
core  

Genetic or familiar forms of primary hyperparathyroidism: description of a case series with familial isolated hyperparathyroidism and review of the literature

open access: yesArchives of Endocrinology and Metabolism
Primaryhyperparathyroidism (PHPT) is a disorder of mineral metabolism caused by inappropriate or excessive secretion of parathyroid hormone. It occurs sporadically in approximately 95% of cases but may also be associated with complex syndromes and/or a ...
Miguel Madeira   +8 more
doaj   +1 more source

Echocardiographic Probability of Pulmonary Hypertension, Cardiac Structural Alterations and All‐Cause Mortality in Maintenance Hemodialysis Patients: A Single‐Center Retrospective Cohort Study With Competing Risk Analysis

open access: yesClinical Cardiology, Volume 49, Issue 7, July 2026.
Using a Fine‑Gray competing risk model accounting for renal transplantation, pulmonary hypertension probability, age, and right ventricular diameter independently predicted mortality in maintenance hemodialysis patients. Risk profiles differed by vascular access, supporting individualized cardiovascular risk stratification.
Jingwen Zhou, Zhenhua Yang, Dongmei Huo
wiley   +1 more source

Aberrant promoter methylation, expression and function of RASSF1A gene in a series of Italian parathyroid tumors [PDF]

open access: yes
Purpose: Aberrant epigenetic features are key events involved in parathyroid tumorigenesis, including DNA methylation, histone methylation, and non-coding RNAs. Ras Association Domain Family Protein1 Isoform A (RASSF1A) and Adenomatous Polyposis of Colon
Tavanti, Giulia Stefania   +13 more
core   +1 more source

Unexpected Cervical Lymph Node Metastasis Revealing TFE3‐Rearranged Renal Cell Carcinoma: Intraoperative Cytologic Clues to an Occult Renal Primary

open access: yesDiagnostic Cytopathology, Volume 54, Issue 7, Page 538-541, July 2026.
ABSTRACT TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare subtype of renal carcinoma that may present diagnostic challenges in cytologic specimens, particularly when metastatic disease represents the initial clinical manifestation. We report the case of a 72‐year‐old man presenting with bulky cervical lymphadenopathy clinically suspicious for
Marc P. Pusztaszeri
wiley   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 13, July 2026.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao   +6 more
wiley   +1 more source

Historical Perspective and Evolutionary Origins of Parathyroid Hormone-Related Protein [PDF]

open access: yes, 2014
After the discovery of parathyroid hormone-related protein (PTHrP) as the cause of the hypercalcemia of malignancy, it was found to be distributed widely in tissues, with its actions driving many physiologic and pathologic conditions.
T Martin (7837733)   +2 more
core  

Coexistence of Multiple Endocrine Neoplasia Type 2B and Centri‐Acinar Emphysema With Alpha‐1 Antitrypsin Deficiency: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 7, July 2026.
We report on a 32‐year‐old female patient with a very rare coexistence of alpha‐1 antitrypsin deficiency (AATD) and multiple endocrine neoplasia type 2B (MEN2B). Both conditions can affect breathing and may hide each other's symptoms, leading to delayed diagnosis.
Mohammad Javad Mohammadifard   +2 more
wiley   +1 more source

Immunohistochemical detection of cell cycle regulators, Fhit protein and apoptotic cells in parathyroid lesions [PDF]

open access: yes, 2003
Objective: The pathological distinction between parathyroid neoplasms and hyperplasias remains difficult. Changes in cell cycle control may lead to clonal proliferation and precede tumorigenesis.
Lazaris, AC   +6 more
core  

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