Acute Pancreatitis Unmasking an Ectopic Parathyroid Adenoma in MEN1 Syndrome and Cushing's Syndrome: A Rare Clinical Convergence. [PDF]
Jafri AD +3 more
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Concurrent papillary thyroid carcinoma, normocalcemic primary hyperparathyroidism, and incidental struma ovarii in a young woman: a case report. [PDF]
Shrestha P +5 more
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Role of vitamin D receptor and calcium sensing receptor in parathyroid cancer. [PDF]
Zhang D +6 more
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Early clinical experience with ⁶⁸Ga-Trivehexin PET/CT in parathyroid adenomas: a proof-of- concept imaging study. [PDF]
Erdogan M +5 more
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PTHrP-associated hypercalcemia in gynecologic malignancies: a scoping review. [PDF]
Bohne SM +6 more
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Differences in quantitative 99mTc-MIBI SPECT/CT parameters between parathyroid adenoma and hyperplasia in secondary hyperparathyroidism. [PDF]
Wang Y +5 more
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A case of suspected ectopic parathyroid chief cell carcinoma in a cat. [PDF]
Kim M +8 more
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Hyperparathyroidism revealed by brown tumors of the jaws: a retrospective case series. [PDF]
Sibari Y +4 more
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Epigenetic processes in sporadic parathyroid neoplasms
Molecular and Cellular Endocrinology, 2018Parathyroid tumors (PTs) are highly variable in their genetic background. Increasing evidence demonstrates that endocrine diseases can be caused by epigenetic alterations. The present review is focused on epigenetic aberrations related to PTs. DNA methylation, posttranslational histone modification, and noncoding RNAs are epigenetic mechanisms involved
Angelica Silva
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EZH2 and ZFX oncogenes in malignant behaviour of parathyroid neoplasms
Several studies reported somatic mutations of many genes (MEN1, CTNNB1, CDKIs and others) in parathyroid adenoma, although with different prevalence. Recently, activating mutations of the EZH2 and ZFX oncogenes were identified in benign parathyroid adenoma by whole exome sequencing. The same mutations had been found in blood and ovary malignant tumours.
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