Culture-specific transcriptional drifts limit the fidelity of organoid infection models. [PDF]
Schweizer PE +20 more
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MicroRNA-mediated regulatory mechanisms in cow's ileum and ileum lymph node in response to Mycobacterium avium subspecies paratuberculosis infection. [PDF]
Wang M +3 more
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Systematic evaluation and optimization of TaqMan qPCR assays targeting F<i>57</i>, ISMAP<i>02</i>, and IS<i>900</i> for multiplex detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>. [PDF]
Bissonnette N +5 more
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When is the best time to test paratuberculosis positivity? Observations from a follow-up study in Hungarian dairy herds. [PDF]
Vass-Bognár B +5 more
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Seroprevalence study of paratuberculosis: Johne's disease, a neglected infection in dairy herds in Apulia (southern Italy). [PDF]
Galgano M +15 more
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Pathogenesis of Paratuberculosis
Veterinary Clinics of North America - Food Animal Practice, 2011Paratuberculosis in ruminants is characterized by oral ingestion of Mycobacterium avium subsp. paratuberculosis (MAP), followed by a long incubation period during which time MAP is able to survive within the host’s macrophages. Initially the infection is held in check by the host’s cell-mediated immune response, but gradually the host loses control of ...
Raymond W Sweeney
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Epidemiology and Economics of Paratuberculosis
Veterinary Clinics of North America - Food Animal Practice, 2011Johne’s disease is the clinical manifestation of Mycobacterium avium subsp. paratuberculosis (MAP) infection and has become widespread since it was first observed in the United States in the early 1900s. MAP is primarily spread through the fecal-oral route, and herds generally become infected by unknowingly purchasing infected animals.
Jason E Lombard
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One vaccine, Mycopar, is licensed for use in US cattle. The vaccine reduces clinical disease and fecal shedding of Mycobacterium avium subsp. paratuberculosis (MAP). The vaccine is indicated for use in herds with a high MAP infection prevalence or herds with limited resources for implementing paratuberculosis control measures. In heavily infected herds,
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