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Genetic Susceptibility to Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 2011Multiple studies indicate that host animal genetics play a role in susceptibility to Mycobacterium avium subsp. paratuberculosis (MAP) infection. However, due to differences in methods used to define MAP-infected animals and controls and differences in methods of genetic analysis, there is as yet no clear consensus on the genes or markers to reliably ...
George E. Shook, Brian W. Kirkpatrick
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Pathogenesis of Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 2011Paratuberculosis in ruminants is characterized by oral ingestion of Mycobacterium avium subsp. paratuberculosis (MAP), followed by a long incubation period during which time MAP is able to survive within the host’s macrophages. Initially the infection is held in check by the host’s cell-mediated immune response, but gradually the host loses control of ...
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Paratuberculosis in Deer [PDF]
, 1992 Paratuberculosis (Johne disease) a chronic infectious disease of ruminants caused by Mycobacterium paratuberculosis, is potentially an important problem in deer farming. Primarily a disease of cattle, sheep, and goats, paratuberculosis is characterized by progressive wasting and diarrhea and granulomatous inflammation of the intestines and mesenteric ...
N. J. L. Gilmour +3 more
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Veterinary Clinics of North America: Food Animal Practice, 2011
One vaccine, Mycopar, is licensed for use in US cattle. The vaccine reduces clinical disease and fecal shedding of Mycobacterium avium subsp. paratuberculosis (MAP). The vaccine is indicated for use in herds with a high MAP infection prevalence or herds with limited resources for implementing paratuberculosis control measures. In heavily infected herds,
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One vaccine, Mycopar, is licensed for use in US cattle. The vaccine reduces clinical disease and fecal shedding of Mycobacterium avium subsp. paratuberculosis (MAP). The vaccine is indicated for use in herds with a high MAP infection prevalence or herds with limited resources for implementing paratuberculosis control measures. In heavily infected herds,
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Paratuberculosis: A Potential Zoonosis?
Veterinary Clinics of North America: Food Animal Practice, 1996Available literature on the controversial role of Mycobacterium paratuberculosis as an etiologic agent in human Crohn's disease is reviewed. Despite almost 15 years of investigation, the question of causal or consequential association between Johne's disease and Crohn's disease continues to linger.
Rodrick J. Chiodini +1 more
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Treatment and Chemoprophylaxis for Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 2011There is no definitive cure for Mycobacterium avium subsp. paratuberculosis (MAP) infections, but several therapeutic agents may be used to alleviate clinical signs of Johne’s disease (JD) in ruminants of significant value. Treatment has to be maintained for the life of the animal and treated animals usually continue to shed MAP.
Marie-Eve Fecteau, Robert H. Whitlock
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Mycobacterium paratuberculosisMonoassociated Nude Mice as a Paratuberculosis Model
Veterinary Pathology, 1991In this study, a paratuberculosis (Johne's disease) model was developed by intragastrically dosing gnotobiotic athymic nude mice with Mycobacterium paratuberculosis. The mice infrequently shed bacilli from their intestinal tracts during the first 4 months after inoculation. Following this time, increasing numbers of M.
A. J. Cooley +3 more
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Paratuberculosis in sheep and goats
Veterinary Microbiology, 2015Paratuberculosis is a chronic insidious, often serious, disease of the global small ruminant industries, mainly causing losses from mortalities and reduced productivity on-farm, interference in trading and, in Australia, profound socio-economic impacts that have periodically compromised harmony of rural communities. The pathogenesis, diagnosis, impacts
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Mycobacterium paratuberculosis
2002: Mycobacterium avium spp. paratuberculosis (MAP) is the causative agent for Johne’s disease, an incurable, chronic, infectious enteritis of ruminants, which results in diarrhoea, weight loss and, ultimately, death. Because of the similar pathology of Johne’s and Crohn’s disease in humans, MAP has also been proposed as the aetiological agent of Crohns’
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Economic Impact of Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 1996The economic impact of paratuberculosis has been estimated in dairy cattle for several areas of the United States and in some other dairy-intensive areas of the world. Losses are primarily due to decreased milk production and unrealized income related to premature culling.
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