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Genetic Susceptibility to Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 2011Multiple studies indicate that host animal genetics play a role in susceptibility to Mycobacterium avium subsp. paratuberculosis (MAP) infection. However, due to differences in methods used to define MAP-infected animals and controls and differences in methods of genetic analysis, there is as yet no clear consensus on the genes or markers to reliably ...
Brian W, Kirkpatrick, George E, Shook
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American Association of Bovine Practitioners Conference Proceedings, 1984
Paratuberculosis is an infection caused by Mycohacterium paratuherculosis. Clinical paratuberculosis is known as Johne's disease. Most animals acquire the infection shortly after birth, but signs of illness usually are not apparent for several years.Paratuberculosis usually is spread from herd to herd by the purchase of infected animals that are not ...
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Paratuberculosis is an infection caused by Mycohacterium paratuherculosis. Clinical paratuberculosis is known as Johne's disease. Most animals acquire the infection shortly after birth, but signs of illness usually are not apparent for several years.Paratuberculosis usually is spread from herd to herd by the purchase of infected animals that are not ...
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Veterinary Clinics of North America: Food Animal Practice, 1996
There is a wide array of accurate and affordable diagnostic tests for Johne’s disease. The challenge is to be clear on the purpose for testing and then use the diagnostic test appropriate to that purpose for the specific animal species or type of business.
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There is a wide array of accurate and affordable diagnostic tests for Johne’s disease. The challenge is to be clear on the purpose for testing and then use the diagnostic test appropriate to that purpose for the specific animal species or type of business.
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Paratuberculosis: A Potential Zoonosis?
Veterinary Clinics of North America: Food Animal Practice, 1996Available literature on the controversial role of Mycobacterium paratuberculosis as an etiologic agent in human Crohn's disease is reviewed. Despite almost 15 years of investigation, the question of causal or consequential association between Johne's disease and Crohn's disease continues to linger.
R J, Chiodini, C A, Rossiter
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Pathogenesis of Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 2011Paratuberculosis in ruminants is characterized by oral ingestion of Mycobacterium avium subsp. paratuberculosis (MAP), followed by a long incubation period during which time MAP is able to survive within the host’s macrophages. Initially the infection is held in check by the host’s cell-mediated immune response, but gradually the host loses control of ...
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Mycobacterium paratuberculosisMonoassociated Nude Mice as a Paratuberculosis Model
Veterinary Pathology, 1991In this study, a paratuberculosis (Johne's disease) model was developed by intragastrically dosing gnotobiotic athymic nude mice with Mycobacterium paratuberculosis. The mice infrequently shed bacilli from their intestinal tracts during the first 4 months after inoculation. Following this time, increasing numbers of M.
H L, Hamilton +3 more
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Immunology: Resistance to Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 1996Disease caused by Mycobacterium paratuberculosis involves a complex interaction of lymphoid and phagocytic cells of the peripheral and mucosal immune responses. For resistance to develop, animals must generate an effective cellular immune response to primary infections as well as multifocal exogenous and endogenous reinfections.
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Economic Impact of Paratuberculosis
Veterinary Clinics of North America: Food Animal Practice, 1996The economic impact of paratuberculosis has been estimated in dairy cattle for several areas of the United States and in some other dairy-intensive areas of the world. Losses are primarily due to decreased milk production and unrealized income related to premature culling.
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Paratuberculosis, Nonhuman Primates
1993Gross lesions are often minimal. Animals usually have a history of chronic wasting and are generally culture negative for other potential enteric pathogens although concomitant bacterial infections may occur. Visible lesions are usually limited to enlarged mesenteric lymph nodes although distended lymphatics may be seen in advanced cases.
Daniel C. Anderson, Harold M. McClure
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Vaccination Against Paratuberculosis (Johne’s Disease)
The Journal of Immunology, 1952Summary A total of 289 lambs, on farms where Paratuberculosis (Johne’s disease) of sheep was prevalent, were vaccinated over a period of 3 years with one or two injections of heat killed Mycobacterium paratuberculosis suspended in mineral oil.
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