Results 191 to 200 of about 3,707 (258)

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

Advanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia, Ava M. Obenaus, Yoeur‐Man T. Mach, Nakul Sridhar, Nathan J. Sniadecki   +4 more
wiley   +1 more source

Prospective association of tobacco retailer density and neighbourhood walkability with youth vaping initiation in California, USA. [PDF]

Tob Control
Harlow AF, Thompson LK, Eckel SP, Leventhal AM, Haley DF, Roberts ME, Cockburn MG, Barrington-Trimis JL.   +7 more
europepmc   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Three-learning strategy particle swarm optimization for air-ground collaborative logistics transportation scheduling problem with pickup and delivery considering customer priorities. [PDF]

Sci Rep
Qi Y, Jiang H, Huang G, Wang F, Ye L.
europepmc   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

Advanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali, Marien Iliza Ochoa Mendoza, Matthew S. Reed, Danylo Mykhalchuk, Annemarie Lang, Joel D. Boerckel, Brian W. Pogue, Sergei A. Vinogradov   +7 more
wiley   +1 more source

Community Food Insecurity Interventions for Adults Living in the United Kingdom: A Scoping Review. [PDF]

Nutr Bull
Smith J, Hodgson P, Williams C, Lake AA, Teasdale SB, Giles EL.   +5 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

30-day readmission risk after hip fracture: a qualitative study in the Midlands, United Kingdom. [PDF]

BMC Geriatr
Sutton E, McMullan C, Reilly H, Miller C, Topping A, Lees Deutsch L.   +5 more
europepmc   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Pulse waveform and current direction alter network-level TMS-induced functional connectivity: Evidence from TMS-EEG.

Neuroimage
Lucarelli D, Guidali G, Guidotti R, Pieramico G, Bolognini N, Romani GL, Pizzella V, Marzetti L.   +7 more
europepmc   +1 more source