Results 41 to 50 of about 632,295 (262)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The effectiveness of the parent-child interaction intervention program based on emotion coaching on the symptoms of children\'s separation anxiety disorder

مجله علوم روانشناختی, 2021
Background: Numerous studies have been conducted on the effectiveness of the parent-child interaction intervention program and the symptoms of separation anxiety disorder in children.
Masoomeh Takhti, AbdolAllah Shafi' Abadi, Atousa Kalantar Hormozi, Noor Ali Farrokhi   +3 more
doaj  

Cooperation and conflict in family decision making [PDF]

, 2008
This study addresses the family dynamics of the decision making process, in particular the issues of cooperation and conflict, in both two parent and lone parent families.
Catterall, M., Hamilton, K.L.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hubungan Kualitas Interaksi Orangtua – Anak Dengan Interaksi Teman Sebaya Di Smk Muhammadiyah 2 Pekanbaru [PDF]

, 2017
The purpose of this research is to know the quality picture of the parent\u27s interaction with the child, to know the description of the interaction of the child with peers and to know the relation of the quality of the parent-child interaction with ...
Arlizon, R. (Raja), Noversi, G. (Giovani), Rosmawati, R. (Rosmawati)   +2 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Parental strees and support of parents of children with spina bifida in Uganda [PDF]

, 2016
Background: Children with disabilities in Sub-Saharan Africa depend for a large part of their functioning on their parent or caregiver. This study explores parental stress and support of parents of children with spina bifida in Uganda.
Bannink Mbazzi, Femke, Idro, Richard, Van Hove, Geert   +2 more
core   +3 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

The specificity, situational modulations, and behavioral correlates of parent-child neural synchrony

Frontiers in Human Neuroscience, 2022
In recent years, aiming to uncover the neural mechanism of parent-child interaction and link it to the children’s social development, a newly developed index, namely, parent-child inter-brain neural synchronization (INS) has attracted growing interest ...
Yi Liu, Jiaxin Li, Qi Wang, Yarong Li
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source