Results 161 to 170 of about 301,002 (240)

Trajectories of Couple Relationship Quality after Childbirth: Does Marriage Matter? [PDF]

Marital quality typically declines following the birth of a (first) child, as parenthood brings new identities and responsibilities for mothers and fathers. Yet, it is unclear whether nonmarital relationship quality follows a similar trajectory.
Marcia J. Carlson
core  

The influence of serotonergic multilocus genetic variants and parent-child relationship on adolescent creativity. [PDF]

Sci Rep
He Z, Zhan L, Zeng Z, Meng L, Liu S, Hu Y.   +5 more
europepmc   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Impact of Parental Narcissistic Personality Disorder on Parent-Child Relationship Quality and Child Well-Being: A Systematic Review. [PDF]

Cureus
Orovou E, Jotautis V, Vousoura E, Koutelekos I, Rigas N, Sarantaki A.   +5 more
europepmc   +1 more source

Computation‐Guided Control of Excited‐State Deactivation through Modulation of Conical‐Intersection Accessibility by Donor–Acceptor Asymmetry in Bridged Stilbene AIE Luminogens

Advanced Science, EarlyView.
Donor–acceptor asymmetry modulates conical‐intersection accessibility and topology in bridged stilbenes, providing mechanistic insight into excited‐state deactivation and aggregation‐induced emission (AIE). ABSTRACT A computation‐guided investigation of asymmetric donor–acceptor bridged stilbenes reveals structure–property relationships governing ...
Takuya Tanaka, Satoshi Suzuki, Hirosato Koyanagi, Kiyoshi Miyata, Riki Iwai, Kazunobu Igawa, Ken Onda, Ben Zhong Tang, Gen‐ichi Konishi   +8 more
wiley   +1 more source

Beyond the feeding relationship: mothers' descriptions of interaction within the mother-child dyad

, 2009
The mother-child relationship is a key determinant of child health. Current evidence acknowledges that impaired mother-child interaction affects social, emotional, cognitive and behavioural development in infants.
Barbard, Penelope Jane
core  

The mechanisms through which the family music environment influences young children's empathy: the mediating role of music emotional contagion and the moderating role of parent-child relationship quality. [PDF]

Front Psychol
Zhou Y.
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

The effect of mindfulness-based stress reduction on self-compassion and parent-child relationship quality in health caregivers. [PDF]

BMC Psychol
Rakhshani T, Bagherfard A, Kamyab A, Jeihooni AK.   +3 more
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source