NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source
Household income and children's mental health outcomes: the mediating role of maternal wellbeing and parent-child relationship quality. [PDF]
Wilson N, Minnis H, McDaid S, Pearce A.
europepmc +2 more sources
Perceptions of early parent-child relationship quality among adult children caring for their parents living with early-stage cognitive impairment: associations with caregiving burden. [PDF]
Wood KA +4 more
europepmc +1 more source
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally +8 more
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Potential‐controlled NH4+‐assisted reversible electrodeposition of molecular metal oxide clusters enables dynamic solution‐to‐solid electron storage. Leveraging this deposition/dissolution reaction chemistry, polyoxometalate‐based hybrid flow batteries are demonstrated as a new platform for deposition‐based electrochemical energy storage.
Ke Wang +3 more
wiley +1 more source
Relations between mind-mindedness, stress and parent-child relationship quality in parents of children with a history of mental health or behavioural difficulties. [PDF]
Larkin F, Fishburn S, Lee Y, Meins E.
europepmc +1 more source
Permanent oxidative dipole (POD) engineering overcomes the electronic uniformity of quinoline‐linked COFs. By enhancing the dipole moment to 2.08 D and lowering exciton binding energy to 20.3 meV, it constructs a robust built‐in electric field and spatially decoupled redox centers. This bypasses inherent kinetic bottlenecks, achieving a 4569 µmol g−1 h−
Yong‐Quan Wu +2 more
wiley +1 more source
The parent-child relationship and child shame and guilt: A meta-analytic systematic review. [PDF]
van Eickels RL +3 more
europepmc +1 more source
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim +5 more
wiley +1 more source

