Results 51 to 60 of about 926,618 (237)

Section 1983 Actions by Family Members Based on Deprivation of the Constitutional Right to Family Association resulting from Wrongful Death: Who has Standing? [PDF]

open access: yes, 1986
Section 1983 initially served to protect individual civil rights, but has now expanded to redressing the deprivation of constitutional rights resulting from wrongful death.
Biesma, Regien   +4 more
core   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

Explaining the Parent-Child Relationship Based on Covid-19 Anxiety with the Intermediary Role of Emotional Security [PDF]

open access: yesخانواده و پژوهش, 2023
This study set out to explain the parent-children relationship based on Covid-19 anxiety with the intermediary role of emotional security. This research had a correlational design.
F. Sadra, S. Imanian, S. Nabizadieh
doaj  

The Historical, Jurisprudential, and Empirical Wisdom of Parental Responsibility Laws [PDF]

open access: yes, 2012
The parent-child relationship is woven deep within historical and contemporary culture, but strong retributive ideals have led to blaming parents because of their presumed vicarious role in juvenile crime.
Brank, Eve M., Scott, Leroy
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Stress Levels and Development: A Phenomenology of Autistic Children and Their Parents [PDF]

open access: yes, 2010
Being a parent means taking on both the joys and struggles that come with it. When a parent discovers that his or her child has been diagnosed with autism spectrum disorder (ASD), the level of stress changes.
Wiggs, Tiffany R
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Post-divorce parental conflict, maternal economic hardship, parent-child relationship and academic achievement among adolescents in divorced families [PDF]

open access: yes, 2013
The purpose of this study was to determine the relationships between post-divorce parental conflict, maternal economic hardship and parent-child relationship with academic achievement in a sample of 800 adolescents of divorced families aged 15to 18 years
Esmaeili, Nooshin Sabour   +1 more
core  

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

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