Results 71 to 80 of about 3,096,886 (286)

Discrepancy between Parents and Children in Reporting of Distress and Impairment: Association with Critical Symptoms [PDF]

, 2014
Background: We examined discrepant parent–child reports of subjective distress and psychosocial impairment. Method: Parent–child pairs (N = 112 pairs) completed the Health Dynamics Inventory at intake for outpatient therapy.
Bein, Laura, Petrik, Megan Lynn, Saunders, Stephen M., Wojcik, James V.   +3 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The role of parental involvement in fundamental movement skills among Hungarian school-aged children

BMC Sports Science, Medicine and Rehabilitation
Background Encouraging physical activity and developing fundamental movement skills (FMS) is crucial for the healthy growth of children. Parental involvement can play a decisive role in shaping children’s physical activity habits; however, few studies ...
Márton István Pelyvás, Klára Kovács
doaj   +1 more source

Intergenerational Progress in Educational Attainment when Institutional Change Really Matters: a Case Study of Franco-Americans vs. French-Speaking Quebeckers [PDF]

Using U.S. and Canadian census data I exploit the massive out migration of approximately I million French-Canadians who moved mainly to New England between 1865 and 1930 to look at how the educational attainment and enrollment patterns of their ...
Daniel Parent
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Industry-Specific Capital and the Wage Profile: Evidence from the NLSY and the PSID [PDF]

Using data from the NLSY (1979-1991) and from the Panel Study of Income Dynamics (PSID, 1981-1987), we seek to determine whether there is any net positive return to tenure with the current employer once we control for industry-specific capital.
Daniel Parent
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Findings from an expert focus group on psychotropic medication deprescribing practices for children and youth with complex needs

Frontiers in Child and Adolescent Psychiatry
IntroductionPsychotropic medication can be effective at stabilizing emotional and behavioural disturbances associated with physiological processes in children and youth.
Laura Theall, Ajit Ninan, Ajit Ninan, Melissa Currie   +3 more
doaj   +1 more source

INTERGENERATIONAL PROGRESS IN EDUCATIONAL ATTAINMENT WHEN INSTITUTIONAL CHANGE REALLY MATTERS: A CASE STUDY OF FRANCO-AMERICANS VS. FRNECH-SPEAKING QUEBECKERS [PDF]

Using U.S. and Canadian census data I exploit the massive out migration of approximately 1 million French-Canadians who moved mainly to New England between 1865 and 1930 to look at how the educationalattainment and enrollment patterns of their ...
Daniel Parent
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source