Results 141 to 150 of about 855,376 (285)

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

Parental attachment and cyberbullying among college students: the mediating role of loneliness and the moderating role of interdependent self. [PDF]

Curr Psychol, 2022
Fang Y, Fan C, Cui J, Zhang X, Zhou T.
europepmc   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

The positive role of parental attachment and communication in Chinese adolescents' health behavior and mental health during COVID-19. [PDF]

J Adolesc, 2022
Yang B, Chen BB, Qu Y, Zhu Y.
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Parental attachment and emotional intelligence mediates the effect of childhood maltreatment on callous-unemotional traits among incarcerated male adolescents. [PDF]

Sci Rep, 2022
Peng J, Lu H, Zhang J, Yuan W, Fang P, Tian J, Wang L.   +6 more
europepmc   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Peer Power! Secure Peer Attachment Mediates the Effect of Parental Attachment on Depressive Withdrawal of Teenagers. [PDF]

Int J Environ Res Public Health, 2022
Muzi S, Rogier G, Pace CS.
europepmc   +1 more source

Parental Closeness and Attachment in Biological and Adopted Children [PDF]

, 2018
From the moment of birth, interactions between parents and the infant form an attachment style that will define the levels of anxiety and avoidance one has in close relationships.
Broxterman, Joel
core  

Coprecipitation‐Enabled Scalable Synthesis of High‐Energy Density Polyanion‐Integrated Disordered Rocksalt Cathodes for Lithium‐Ion Batteries

Advanced Energy Materials, EarlyView.
A coprecipitation‐enabled solid‐state route enables scalable synthesis of the metastable polyanion‐integrated disordered rocksalt cathode, Li1.67Mn1.5P0.17O4, without mechanochemical phase formation or post‐synthesis pulverization. Coprecipitation establishes local Mn–P–O integration in the precursor, while eutectic LiOH/LiNO3‐assisted lithiation ...
Hsi Chen, Yung‐An Chen, Chen Chang, Frances M. Ross, Yimeng Huang, Ju Li   +5 more
wiley   +1 more source