Results 111 to 120 of about 370,073 (312)

Ethical decision-making regarding infant viability: A discussion [PDF]

, 2016
© The Author(s) 2016. Background: There are no universally agreed rules of healthcare ethics. Ethical decisions and standards tend to be linked to professional codes of practice when dealing with complex issues. Objectives: This paper aims to explore the
Kelly, Janet, Welch, Emma
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Adolescents’ appraisal and disclosure mediate the links between parental practices and adolescents’ digital citizenship behaviors

Humanities & Social Sciences Communications
Parenting-related factors are associated with adolescents’ online behaviors. However, the relationship between parenting and digital citizenship behaviors in adolescents and the variables underlying these relations must be clarified.
Agustín Morales-Álvarez, Angel Alberto Valdés-Cuervo, Lizeth Guadalupe Parra-Pérez, Fernanda Inéz García-Vázquez, María Fernanda Durón-Ramos   +4 more
doaj   +1 more source

Parental involvement in children’s homework during the COVID-19-related remote education: the role of parental motivational beliefs and emotions

Psychology, Society & Education
The remote education during the COVID-19 pandemic was a novel educational situation for children and parents. The study investigated (1) changes in parental involvement in children’s homework (autonomy support, control, and interference) during school ...
Konstantina Falanga, Tania Vieites, Eleftheria Gonida   +2 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

The Controlling Interpersonal Style in a Coaching Context: Development and Initial Validation of a Psychometric Scale [PDF]

, 2010
This article outlines the development and initial validation of the Controlling Coach Behaviors Scale (CCBS), a multidimensional self-report measure designed to assess sports coaches’ controlling interpersonal style from the perspective of self ...
Bartholomew, Kimberley, Ntoumanis, Nikos, Thøgersen-Ntoumani, Cecilie   +2 more
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Role of parental autonomy support on self-determination in influencing diet and exercise motivation in older adolescents

Nursing: Research and Reviews, 2013
Shannon A Morrison, Carol J Dashiff, David E Vance School of Nursing, University of Alabama, Birmingham, AL, USA Abstract: Parental influence to promote autonomy and self-determination in their children as they grow up may also motivate them to exercise ...
Morrison SA, Dashiff CJ, Vance DE
doaj  

PERCEPTION OF PARENTAL SUPPORT BY DEAF AND HARD-OF-HEARING STUDENTS

Human Research in Rehabilitation, 2019
The aim of the paper was to determine the perception of parental support and understanding by deaf and hard-of-hearing students. The sample consisted of 47 deaf and hard-of-hearing students, both genders, with an average age of 16 ± 1.27 years ...
Meliha Povlakić Hadžiefendić, Esad H. Mahmutović , Husnija Hasanbegović   +2 more
doaj   +1 more source