microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez +5 more
wiley +1 more source
United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals. [PDF]
Soliman HK, Coughlan JM.
europepmc +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
RNA-directed DNA methylation as a weapon in parental conflict. [PDF]
Cao D.
europepmc +1 more source
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi +4 more
wiley +1 more source
Inter-parental conflict and empathy in early adolescence as predictors of dating violence perpetration in adolescence and adulthood. [PDF]
Espinoza CN, Goering M, Mrug S.
europepmc +1 more source
Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba +5 more
wiley +1 more source
Parental conflict driven regulation of endosperm cellularization by a family of Auxin Response Factors. [PDF]
Butel N +4 more
europepmc +1 more source
Challenging Behavior, Parental Conflict and Community Violence in Students with Aggressive Behavior. [PDF]
Valdés Cuervo AA +3 more
europepmc +1 more source

