Results 241 to 250 of about 137,241 (299)

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation

Advanced Science, EarlyView.
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi, Xinwei Qiao, Yue Hu, Minjie Wang, Shaojie Yu, Zihan Gong, Yuxin Rao, Hui Zheng, Siting Chen, Lin Li, Rong Fu, Tao Liang, Jin Yao, Xiaobing Jiang, Junjun Li   +14 more
wiley   +1 more source

The effects of parental mindfulness on preschoolers' prosocial behavior: the chain mediating model of marital quality, authoritative parenting, and the sex difference. [PDF]

Front Psychol
Zhang M, Qiao L, Zhang Y, Li L, Zhao S, Akintunde TY, Yang X.   +6 more
europepmc   +1 more source

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Challenges faced by parents in preventing online child sexual exploitation and abuse: a mixed methods systematic review. [PDF]

Front Public Health
Punjani N, Hussain A, Yan W, Hartling L, Scott SD, Elgaweesh F, Kennedy M.   +6 more
europepmc   +1 more source

Developing an inventory to Assess Parental concerns and Enable child dental Registration (DAPER):Phase 3 Report: Field trial of the PDCS using the CHATTERBOX intervention [PDF]

, 2013
Freeman, Ruth, Nanjappa, Sucharita
core   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

How parental autonomy support fosters adolescent future orientation: the mediating roles of growth mindset and hope, moderated by peer relationships. [PDF]

Front Psychol
Li X, Awan AUR, Chen T.
europepmc   +1 more source

Parental kinship influences global methylation and epigenetic age estimation in Peromyscus. [PDF]

Genetics
Huynh-Dam KT, Jaeger C, Chatzistamou I, Horvath S, Kiaris H.   +4 more
europepmc   +1 more source

Revising Parental Burnout Theory: Toward a Differentiation of Sleep-Related Burnout Subtypes. [PDF]

Children (Basel)
Anders R, Breton A, Lecuelle F, Havy M, Brunel L, Gustin MP, Franco P, Putois B.   +7 more
europepmc   +1 more source

The Mediating Role of Screen-Based Sedentary Behaviors in the Association of Parental Educational Level and BMI with Preschoolers' Ultra-Processed Food Consumption. [PDF]

Nutrients
Machado-Rodrigues AM, Fernandes HM, Stabelini Neto A, Dos Santos EA, Tur JA, Padez C, Rodrigues D.   +6 more
europepmc   +1 more source